OpenClaim

Glasdegib Side Effects

The most commonly reported side effects of glasdegib include death, febrile neutropenia, and pneumonia, based on 470 FDA adverse event reports from 2011 to 2025. 2.1% of reports found the drug to be ineffective.

Glasdegib side effects

Percentages show how often each reaction appears relative to total reports for glasdegib.

1
Death23.4%110
2
Febrile Neutropenia14.5%68
3
Pneumonia10.4%49
4
Off Label Use7.2%34
5
Neoplasm Progression6.0%28
6
Neutropenia4.7%22
7
Sepsis3.2%15
8
Toxicity To Various Agents2.8%13
9
Electrocardiogram Qt Prolonged2.6%12
10
Product Use In Unapproved Indication2.3%11
11
Septic Shock2.3%11
12
Pyrexia2.1%10
13
Decreased Appetite2.1%10
14
Infection2.1%10
15
Drug Ineffective2.1%10

These are voluntary reports and do not establish that glasdegib caused these reactions.

Report severity

93.4%Serious439 reports
47.9%Hospitalizations225 reports
40.4%Fatal190 reports

Seriousness is determined by the reporter, not by OpenClaim.

Glasdegib drug interactions

Other drugs that appear in adverse event reports alongside glasdegib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cytarabine27.2%128
2
Azacitidine23.2%109
3
Daunorubicin16.0%75
4
Venetoclax4.3%20
5
Temozolomide3.2%15
6
Fluticasone3.0%14
7
Vilanterol-trifenatate3.0%14
8
Apixaban3.0%14
9
Levothyroxine-sodium2.8%13
10
Umeclidinium-bromide2.8%13
11
Tamsulosin-hydrochloride2.8%13
12
Bisoprolol-fumarate2.8%13
13
Perindopril2.8%13
14
Decitabine1.7%8
15
Cyclosporine1.1%5

Taken alongside

1
Acyclovir10.6%50
2
Allopurinol9.1%43
3
Acetaminophen8.9%42
4
Levofloxacin8.7%41
5
Ondansetron8.1%38
6
Pantoprazole-sodium7.4%35
7
Cytarabine6.4%30
8
Furosemide5.7%27
9
Posaconazole5.7%27
10
Amlodipine5.3%25
11
Levothyroxine-sodium5.1%24
12
Omeprazole4.9%23
13
Fluconazole4.7%22
14
Dexamethasone4.5%21
15
Potassium-chloride4.3%20

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports glasdegib side effects

34.5% of glasdegib adverse event reports involve female patients and 58.1% involve male patients. The largest age group is elderly at 69%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.5%
Male58.1%
Unknown7.4%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6430.7%
65+69.3%

What is glasdegib used for

Conditions and purposes for which patients were taking glasdegib when the adverse event was reported.

Acute LeukaemiaAcute Monocytic LeukaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RecurrentAcute Myeloid Leukaemia RefractoryAnaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia (in Remission)Acute Myeloid Leukaemia RefractoryChronic Graft Versus Host DiseaseChronic Myeloid LeukaemiaChronic Myelomonocytic LeukaemiaChemotherapyChronic Graft Versus Host DiseaseGlioblastoma

Showing 15 of 31 indications

Glasdegib brand names and reporting trend

Glasdegib is sold under the brand name Daurismo.

Brand names

Daurismo352

Quarterly reports (20112025)

2011202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking glasdegib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.