OpenClaim

Gemfibrozil Side Effects

The most commonly reported side effects of gemfibrozil include dyspnoea, fatigue, and diarrhoea, based on 104,269 FDA adverse event reports from 2004 to 2025. 3.6% of reports found the drug to be ineffective.

Gemfibrozil side effects

Percentages show how often each reaction appears relative to total reports for gemfibrozil.

1
Dyspnoea4.4%4,601
2
Fatigue4.2%4,391
3
Diarrhoea3.6%3,710
4
Drug Ineffective3.6%3,702
5
Dizziness3.5%3,680
6
Nausea3.3%3,469
7
Acute Kidney Injury3.3%3,465
8
Drug Interaction3.2%3,332
9
Fall3.1%3,189
10
Anaemia3.0%3,146
11
Off Label Use2.9%3,033
12
Asthenia2.7%2,814
13
Death2.6%2,688
14
Myocardial Infarction2.5%2,623
15
Headache2.5%2,568

These are voluntary reports and do not establish that gemfibrozil caused these reactions.

Report severity

84.1%Serious87,654 reports
46.0%Hospitalizations47,942 reports
10.4%Fatal10,829 reports

Seriousness is determined by the reporter, not by OpenClaim.

Gemfibrozil drug interactions

Other drugs that appear in adverse event reports alongside gemfibrozil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aspirin10.9%11,334
2
Atorvastatin-calcium4.1%4,279
3
Omeprazole2.9%3,012
4
Apixaban2.7%2,843
5
Pantoprazole-sodium2.7%2,819
6
Rivaroxaban2.4%2,471
7
Metformin2.3%2,400
8
Simvastatin2.2%2,332
9
Amlodipine2.1%2,189
10
Lenalidomide2.1%2,183
11
Lansoprazole2.0%2,137
12
Ramipril2.0%2,131
13
Adalimumab2.0%2,113
14
Esomeprazole2.0%2,048
15
Rosuvastatin1.9%1,956

Taken alongside

1
Aspirin26.8%27,923
2
Atorvastatin-calcium23.7%24,721
3
Metoprolol15.2%15,893
4
Furosemide13.9%14,544
5
Amlodipine12.9%13,495
6
Metformin11.5%12,033
7
Acetaminophen11.4%11,882
8
Pantoprazole-sodium11.0%11,430
9
Levothyroxine-sodium9.7%10,079
10
Simvastatin9.6%10,059
11
Omeprazole9.4%9,799
12
Lisinopril9.1%9,521
13
Insulin8.8%9,166
14
Bisoprolol-fumarate8.5%8,822
15
Rosuvastatin7.4%7,698

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports gemfibrozil side effects

37.6% of gemfibrozil adverse event reports involve female patients and 51.6% involve male patients. The largest age group is elderly at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female37.6%
Male51.6%
Unknown10.8%

Age group

< 20.2%
2–110.2%
12–170.1%
18–6433.7%
65+65.8%

What is gemfibrozil used for

Conditions and purposes for which patients were taking gemfibrozil when the adverse event was reported.

Abdominal DistensionAbdominal Pain UpperAbdominal Wall HaematomaAcute Cardiac EventAcute Coronary SyndromeAcute Left Ventricular FailureAcute Myeloid LeukaemiaAcute Myocardial InfarctionAcute Myocardial Infarction, Of Inferoposterior WallAdjuvant TherapyAdverse EventAdverse ReactionAgitationAkinesiaAllergy Test

Showing 15 of 1,179 indications

Gemfibrozil brand names and reporting trend

Gemfibrozil is sold under the brand name Gemfibrozil.

Brand names

Gemfibrozil11,855

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking gemfibrozil with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.