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Garadacimab Side Effects

The most commonly reported side effects of garadacimab include hereditary angioedema, abdominal pain, and swelling, based on 145 FDA adverse event reports from 2007 to 2025. 13.8% of reports found the drug to be ineffective.

Garadacimab side effects

Percentages show how often each reaction appears relative to total reports for garadacimab.

1
Hereditary Angioedema63.4%92
2
Drug Ineffective13.8%20
3
Abdominal Pain9.7%14
4
Swelling6.9%10
5
Injection Site Pain6.2%9
6
Stress6.2%9
7
Weight Decreased6.2%9
8
Off Label Use5.5%8
9
Headache5.5%8
10
Weight Increased5.5%8
11
Product Use Issue4.8%7
12
Pain4.1%6
13
Malaise4.1%6
14
Abdominal Distension4.1%6
15
Gastrointestinal Disorder4.1%6

These are voluntary reports and do not establish that garadacimab caused these reactions.

Report severity

83.4%Serious121 reports
19.3%Hospitalizations28 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Garadacimab drug interactions

Other drugs that appear in adverse event reports alongside garadacimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Icatibant-acetate4.8%7
2
Lanadelumab-flyo4.8%7
3
Ecallantide2.8%4
4
Sebetralstat2.1%3
5
Omalizumab2.1%3
6
Adalimumab0.7%1
7
Corticotropin0.7%1
8
Epinephrine0.7%1
9
Benralizumab0.7%1

Taken alongside

1
Icatibant-acetate19.3%28
2
Epinephrine8.3%12
3
Lanadelumab-flyo6.2%9
4
Sodium-chloride4.1%6
5
Sterile4.1%6
6
Sebetralstat4.1%6
7
Albuterol2.1%3
8
Famotidine2.1%3
9
Atorvastatin-calcium2.1%3
10
Heparin2.1%3
11
Omalizumab2.1%3
12
Levothyroxine-sodium1.4%2
13
Danazol1.4%2
14
Cetirizine-hydrochloride1.4%2
15
Amlodipine1.4%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports garadacimab side effects

70.3% of garadacimab adverse event reports involve female patients and 21.4% involve male patients. The largest age group is adult at 78%. These figures reflect who reports side effects, not underlying risk.

Sex

Female70.3%
Male21.4%
Unknown8.3%

Age group

< 20.0%
2–110.0%
12–175.3%
18–6477.9%
65+16.8%

What is garadacimab used for

Conditions and purposes for which patients were taking garadacimab when the adverse event was reported.

Drug Use For Unknown IndicationHereditary AngioedemaHereditary Angioedema With C1 Esterase Inhibitor DeficiencyHereditary Angioedema With Normal C1 Esterase InhibitorImmune System DisorderImmunodeficiencyProduct Used For Unknown IndicationProphylaxis

Garadacimab brand names and reporting trend

Garadacimab is sold under the brand name Andembry.

Brand names

Andembry69

Quarterly reports (20072025)

20072025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking garadacimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.