OpenClaim

Galcanezumab Side Effects

The most commonly reported side effects of galcanezumab include injection site pain, underdose, and migraine, based on 30,251 FDA adverse event reports from 2012 to 2025. 6.5% of reports found the drug to be ineffective.

Galcanezumab side effects

Percentages show how often each reaction appears relative to total reports for galcanezumab.

1
Injection Site Pain23.3%7,037
2
Underdose9.7%2,948
3
Migraine9.7%2,934
4
Headache7.9%2,385
5
Drug Ineffective6.5%1,955
6
Product Dose Omission Issue5.7%1,725
7
Injection Site Haemorrhage5.0%1,510
8
Injection Site Erythema3.6%1,097
9
Accidental Underdose3.5%1,070
10
Incorrect Dose Administered2.8%860
11
Nausea2.7%814
12
Injection Site Pruritus2.7%811
13
Injection Site Swelling2.7%802
14
Fatigue2.5%746
15
Injection Site Reaction2.4%726

These are voluntary reports and do not establish that galcanezumab caused these reactions.

Report severity

12.9%Serious3,890 reports
3.7%Hospitalizations1,111 reports
0.3%Fatal87 reports

Seriousness is determined by the reporter, not by OpenClaim.

Galcanezumab drug interactions

Other drugs that appear in adverse event reports alongside galcanezumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Erenumab-aooe1.4%410
2
Dupilumab0.7%222
3
Rimegepant0.7%209
4
Sodium-oxybate0.6%171
5
Fremanezumab-vfrm0.4%126
6
Onabotulinumtoxina0.4%106
7
Eptinezumab-jjmr0.3%95
8
Topiramate0.3%88
9
Adalimumab0.2%70
10
Ubrogepant0.2%67
11
Tirzepatide0.2%65
12
Ocrelizumab0.2%61
13
Calcium-oxybate0.2%59
14
Magnesium-oxybate0.2%59
15
Potassium-oxybate0.2%59

Taken alongside

1
Sumatriptan3.5%1,048
2
Acetaminophen3.0%917
3
Topiramate2.9%869
4
Ergocalciferol2.6%776
5
Gabapentin2.1%635
6
Rizatriptan-benzoate2.1%629
7
Onabotulinumtoxina1.9%589
8
Rimegepant1.8%545
9
Levothyroxine-sodium1.7%518
10
Ondansetron1.7%512
11
Ubrogepant1.6%497
12
Albuterol1.6%488
13
Ibuprofen1.5%457
14
Fluticasone1.5%446
15
Aspirin1.4%438

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports galcanezumab side effects

77.3% of galcanezumab adverse event reports involve female patients and 11.5% involve male patients. The largest age group is adult at 87%. These figures reflect who reports side effects, not underlying risk.

Sex

Female77.3%
Male11.5%
Unknown11.2%

Age group

< 2<0.1%
2–11<0.1%
12–170.7%
18–6486.6%
65+12.5%

What is galcanezumab used for

Conditions and purposes for which patients were taking galcanezumab when the adverse event was reported.

Abdominal MigraineAccidental Exposure To ProductAngiopathyArthropathyAsthmaAccidental Exposure To Product By ChildAdverse Drug ReactionAnxietyAphasiaArthralgiaAsthmaAuraAutonomic Nervous System ImbalanceBasilar MigraineBrain Neoplasm

Showing 15 of 136 indications

Galcanezumab brand names and reporting trend

Galcanezumab is sold under the brand name Emgality.

Brand names

Emgality740

Quarterly reports (20122025)

20122016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking galcanezumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.