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Gadoteridol Side Effects

The most commonly reported side effects of gadoteridol include nephrogenic systemic fibrosis, pain, and anxiety, based on 1,748 FDA adverse event reports from 2004 to 2025.

Gadoteridol side effects

Percentages show how often each reaction appears relative to total reports for gadoteridol.

1
Nephrogenic Systemic Fibrosis25.9%453
2
Pain20.4%356
3
Anxiety13.3%232
4
Emotional Distress12.0%209
5
Mobility Decreased10.2%179
6
Fibrosis10.2%178
7
General Physical Health Deterioration10.1%177
8
Injury9.6%167
9
Scar8.9%156
10
Nephrogenic Systemic Fibrosis8.4%147
11
Skin Induration8.2%144
12
Skin Hypertrophy8.0%140
13
Skin Tightness7.4%129
14
Oedema Peripheral6.5%114
15
Joint Range Of Motion Decreased6.4%111

These are voluntary reports and do not establish that gadoteridol caused these reactions.

Report severity

84.3%Serious1,474 reports
20.7%Hospitalizations361 reports
9.4%Fatal164 reports

Seriousness is determined by the reporter, not by OpenClaim.

Gadoteridol drug interactions

Other drugs that appear in adverse event reports alongside gadoteridol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Gadodiamide33.7%589
2
Gadopentetate-dimeglumine33.3%582
3
Gadobenate-dimeglumine29.3%512
4
Gadoversetamide27.6%483
5
Gadoterate-meglumine2.4%42
6
Gadobutrol1.1%20
7
Meglumine1.0%17
8
Ferumoxytol0.5%9
9
Bevacizumab0.4%7
10
Moxifloxacin-hydrochloride0.3%6
11
Paclitaxel0.3%6
12
Carbamazepine0.3%5
13
Gadoxetate-disodium0.3%5
14
Ivermectin0.3%5
15
Hydrocortisone0.3%5

Taken alongside

1
Estropipate9.5%166
2
Sevelamer9.5%166
3
Prednisone8.4%147
4
Metoprolol8.4%147
5
Warfarin8.0%139
6
Amlodipine7.2%125
7
Furosemide7.0%122
8
Acetaminophen5.8%102
9
Calcium-acetate5.7%100
10
Gabapentin5.5%97
11
Aspirin5.5%96
12
Levothyroxine-sodium4.9%86
13
Insulin4.6%80
14
Lisinopril4.2%74
15
Atorvastatin-calcium4.2%73

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports gadoteridol side effects

54.3% of gadoteridol adverse event reports involve female patients and 40.7% involve male patients. The largest age group is adult at 68%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.3%
Male40.7%
Unknown4.9%

Age group

< 20.3%
2–111.8%
12–171.4%
18–6467.8%
65+28.7%

What is gadoteridol used for

Conditions and purposes for which patients were taking gadoteridol when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAbscessAdrenal InsufficiencyAmnesiaAneurysmAngiogramAngiomyolipomaAngioplastyAphasiaArteriogramArteriogram CarotidArteriogram CoronaryArteriogram Renal

Showing 15 of 221 indications

Gadoteridol brand names and reporting trend

Gadoteridol is sold under the brand name Prohance.

Brand names

Prohance146

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking gadoteridol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.