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Furosemide Side Effects

The most commonly reported side effects of furosemide include dyspnoea, acute kidney injury, and fatigue, based on 404,620 FDA adverse event reports from 2004 to 2025. 3.1% of reports found the drug to be ineffective.

Furosemide side effects

Percentages show how often each reaction appears relative to total reports for furosemide.

1
Dyspnoea6.0%24,349
2
Acute Kidney Injury4.7%19,180
3
Fatigue4.4%17,964
4
Diarrhoea4.2%17,085
5
Death4.0%16,378
6
Nausea3.7%14,917
7
Off Label Use3.5%14,015
8
Fall3.4%13,748
9
Pneumonia3.3%13,474
10
Drug Ineffective3.1%12,450
11
Hypotension3.0%12,084
12
Asthenia3.0%12,002
13
Dizziness2.9%11,848
14
Headache2.8%11,239
15
Pain2.5%10,270

These are voluntary reports and do not establish that furosemide caused these reactions.

Report severity

81.8%Serious330,950 reports
49.4%Hospitalizations199,852 reports
15.7%Fatal63,542 reports

Seriousness is determined by the reporter, not by OpenClaim.

Furosemide drug interactions

Other drugs that appear in adverse event reports alongside furosemide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide4.2%16,821
2
Omeprazole3.1%12,377
3
Treprostinil2.7%11,082
4
Apixaban2.6%10,581
5
Pantoprazole-sodium2.5%10,200
6
Aspirin2.5%10,028
7
Valsartan2.4%9,723
8
Spironolactone2.3%9,487
9
Ambrisentan2.2%8,962
10
Metformin2.2%8,745
11
Rivaroxaban2.1%8,669
12
Esomeprazole2.1%8,629
13
Warfarin2.0%8,030
14
Adalimumab2.0%7,935
15
Lansoprazole1.8%7,412

Taken alongside

1
Aspirin21.5%86,807
2
Acetaminophen17.0%68,805
3
Atorvastatin-calcium15.2%61,450
4
Metoprolol14.6%59,011
5
Levothyroxine-sodium13.7%55,318
6
Omeprazole13.1%52,974
7
Spironolactone12.7%51,233
8
Potassium-chloride12.2%49,546
9
Amlodipine12.1%48,947
10
Albuterol11.7%47,524
11
Ergocalciferol11.2%45,267
12
Pantoprazole-sodium10.4%41,984
13
Insulin10.3%41,857
14
Lisinopril10.0%40,363
15
Metformin9.6%38,772

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports furosemide side effects

51.7% of furosemide adverse event reports involve female patients and 41.6% involve male patients. The largest age group is elderly at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female51.7%
Male41.6%
Unknown6.7%

Age group

< 20.9%
2–110.8%
12–170.6%
18–6433.2%
65+64.5%

What is furosemide used for

Conditions and purposes for which patients were taking furosemide when the adverse event was reported.

5q Minus SyndromeAbdominal DistensionAbdominal InfectionAbdominal PainAbdominal Pain UpperAbdominal SepsisAbnormal Weight GainAbscess DrainageAccidental ExposureAcid Base BalanceAcromegalyAcute Chest SyndromeAcute Coronary SyndromeAcute Graft Versus Host DiseaseAcute Hepatic Failure

Showing 15 of 2,173 indications

Furosemide brand names and reporting trend

Furosemide is sold under the brand name Lasix.

Brand names

Lasix295,688

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking furosemide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.