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Fosamprenavir Side Effects

The most commonly reported side effects of fosamprenavir include pain, emotional distress, and anxiety, based on 1,117 FDA adverse event reports from 2004 to 2025.

Fosamprenavir side effects

Percentages show how often each reaction appears relative to total reports for fosamprenavir.

1
Pain14.1%157
2
Emotional Distress13.6%152
3
Anxiety12.5%140
4
Anhedonia11.7%131
5
Chronic Kidney Disease7.3%82
6
Osteoporosis6.0%67
7
Bone Density Decreased5.6%62
8
Renal Failure4.7%52
9
Economic Problem4.7%52
10
Depression4.5%50
11
Rash4.4%49
12
Renal Impairment4.4%49
13
Drug Exposure During Pregnancy4.3%48
14
Nausea3.9%44
15
Diarrhoea3.8%43

These are voluntary reports and do not establish that fosamprenavir caused these reactions.

Report severity

76.2%Serious851 reports
28.3%Hospitalizations316 reports
6.4%Fatal71 reports

Seriousness is determined by the reporter, not by OpenClaim.

Fosamprenavir drug interactions

Other drugs that appear in adverse event reports alongside fosamprenavir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tenofovir33.4%373
2
Ritonavir29.7%332
3
Lamivudine28.6%319
4
Emtricitabine27.3%305
5
Abacavir19.1%213
6
Zidovudine14.9%166
7
Efavirenz11.8%132
8
Raltegravir-potassium7.9%88
9
Lopinavir6.4%72
10
Atazanavir-sulfate5.9%66
11
Stavudine5.6%63
12
Enfuvirtide5.5%61
13
Didanosine5.4%60
14
Darunavir4.4%49
15
Cobicistat3.5%39

Taken alongside

1
Ritonavir39.5%441
2
Tenofovir31.3%350
3
Emtricitabine26.1%292
4
Lamivudine25.5%285
5
Abacavir17.0%190
6
Zidovudine15.0%168
7
Raltegravir-potassium10.6%118
8
Efavirenz9.8%109
9
Dolutegravir9.8%109
10
Darunavir9.4%105
11
Sulfamethoxazole9.3%104
12
Lopinavir9.0%101
13
Atazanavir-sulfate8.7%97
14
Trimethoprim8.0%89
15
Didanosine7.3%81

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports fosamprenavir side effects

25.1% of fosamprenavir adverse event reports involve female patients and 64.6% involve male patients. The largest age group is adult at 88%. These figures reflect who reports side effects, not underlying risk.

Sex

Female25.1%
Male64.6%
Unknown10.3%

Age group

< 22.6%
2–110.6%
12–170.6%
18–6487.7%
65+8.6%

What is fosamprenavir used for

Conditions and purposes for which patients were taking fosamprenavir when the adverse event was reported.

Acquired Immunodeficiency SyndromeAntiretroviral TherapyAntiviral ProphylaxisAntiviral TreatmentAcquired Immunodeficiency SyndromeDrug Exposure During PregnancyDrug Use For Unknown IndicationFoetal Exposure During PregnancyHiv InfectionHiv Test PositiveHiv InfectionHypertensionIll-defined DisorderMaternal Exposure Timing UnspecifiedMedical Observation

Showing 15 of 21 indications

Fosamprenavir brand names and reporting trend

Fosamprenavir is sold under the brand name Fosamprenavir Calcium.

Brand names

Fosamprenavir Calcium166

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking fosamprenavir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.