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Flurbiprofen Side Effects

The most commonly reported side effects of flurbiprofen include off label use, angioedema, and acute kidney injury, based on 2,141 FDA adverse event reports from 2004 to 2025. 4.8% of reports found the drug to be ineffective.

Flurbiprofen side effects

Percentages show how often each reaction appears relative to total reports for flurbiprofen.

1
Off Label Use5.0%108
2
Drug Ineffective4.8%103
3
Angioedema4.5%97
4
Acute Kidney Injury3.5%75
5
Urticaria3.4%73
6
Nausea3.0%64
7
Drug Hypersensitivity2.9%63
8
Pain2.8%61
9
Arthralgia2.8%61
10
Pneumonia2.8%59
11
Dyspnoea2.4%52
12
Pyrexia2.4%51
13
Fatigue2.3%49
14
Diarrhoea2.2%48
15
Rash2.2%48

These are voluntary reports and do not establish that flurbiprofen caused these reactions.

Report severity

86.8%Serious1,859 reports
40.4%Hospitalizations865 reports
12.1%Fatal259 reports

Seriousness is determined by the reporter, not by OpenClaim.

Flurbiprofen drug interactions

Other drugs that appear in adverse event reports alongside flurbiprofen. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ibuprofen7.2%154
2
Acetaminophen5.7%123
3
Lidocaine4.8%102
4
Dexamethasone4.4%94
5
Adalimumab4.1%88
6
Phenylephrine3.7%80
7
Methotrexate3.7%79
8
Cyclopentolate-hydrochloride3.5%76
9
Sodium-chloride3.5%76
10
Diclofenac3.5%76
11
Etanercept3.3%70
12
Potassium-chloride2.9%63
13
Calcium-chloride2.9%62
14
Magnesium-chloride2.9%62
15
Sodium-acetate2.9%62

Taken alongside

1
Acetaminophen16.0%342
2
Aspirin8.8%189
3
Furosemide8.5%183
4
Prednisone8.3%178
5
Omeprazole7.8%168
6
Methotrexate6.9%148
7
Folic-acid6.9%147
8
Dexamethasone6.0%129
9
Amlodipine5.8%125
10
Potassium-chloride5.6%120
11
Levothyroxine-sodium5.4%116
12
Famotidine5.2%112
13
Tramadol-hydrochloride5.1%110
14
Lidocaine5.1%109
15
Lansoprazole5.0%107

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports flurbiprofen side effects

57.0% of flurbiprofen adverse event reports involve female patients and 33.3% involve male patients. The largest age group is adult at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.0%
Male33.3%
Unknown9.6%

Age group

< 21.0%
2–112.2%
12–176.0%
18–6457.0%
65+33.8%

What is flurbiprofen used for

Conditions and purposes for which patients were taking flurbiprofen when the adverse event was reported.

Abdominal PainAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAdverse EventAllergy TestAnaesthesiaAnaesthesia ProcedureAnalgesic EffectAnalgesic Intervention Supportive TherapyAnalgesic TherapyAngina PectorisAnkylosing SpondylitisAntiinflammatory TherapyAntipyresisAppendicitis

Showing 15 of 246 indications

Flurbiprofen brand names and reporting trend

Flurbiprofen is sold under brand names including Flurbiprofen, Flurbiprofen Sodium.

Brand names

Flurbiprofen2,030
Flurbiprofen Sodium114

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking flurbiprofen with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.