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Fluoroestradiol Side Effects

The most commonly reported side effects of fluoroestradiol include no adverse event, false negative investigation result, and product with quality issue administered, based on 13 FDA adverse event reports from 2023 to 2025. 15.4% of reports found the drug to be ineffective.

Fluoroestradiol side effects

Percentages show how often each reaction appears relative to total reports for fluoroestradiol.

1
No Adverse Event61.5%8
2
False Negative Investigation Result30.8%4
3
Drug Ineffective15.4%2
4
Product With Quality Issue Administered15.4%2
5
Inappropriate Release Of Product For Distribution15.4%2
6
Seizure15.4%2
7
Hot Flush7.7%1
8
Hyperhidrosis7.7%1
9
False Positive Radioisotope Investigation Result7.7%1
10
False Negative Radioisotope Investigation Result7.7%1
11
Radiation Necrosis7.7%1
12
Gait Disturbance7.7%1
13
Metastases To Meninges7.7%1
14
Lethargy7.7%1
15
Mental Status Changes7.7%1

These are voluntary reports and do not establish that fluoroestradiol caused these reactions.

Report severity

15.4%Serious2 reports
0.0%Hospitalizations0 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Fluoroestradiol drug interactions

Other drugs that appear in adverse event reports alongside fluoroestradiol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Taken alongside

1
Abemaciclib7.7%1
2
Letrozole7.7%1
3
Lorazepam7.7%1
4
Fulvestrant7.7%1
5
Palbociclib7.7%1
6
Trastuzumab7.7%1
7
Amlodipine7.7%1
8
Carvedilol7.7%1
9
Ferrous-sulfate7.7%1
10
Gabapentin7.7%1
11
Hydralazine-hydrochloride7.7%1
12
Hydrochlorothiazide7.7%1
13
Hydromorphone-hydrochloride7.7%1
14
Lidocaine7.7%1
15
Prilocaine7.7%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports fluoroestradiol side effects

76.9% of fluoroestradiol adverse event reports involve female patients and 0.0% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female76.9%
Male0.0%
Unknown23.1%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6466.7%
65+33.3%

What is fluoroestradiol used for

Conditions and purposes for which patients were taking fluoroestradiol when the adverse event was reported.

Breast Cancer FemaleDiagnostic ProcedureInvasive Lobular Breast CarcinomaPositron Emission Tomogram

Fluoroestradiol brand names and reporting trend

Quarterly reports (20232025)

202320242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking fluoroestradiol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.