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Flotufolastat Side Effects

The most commonly reported side effects of flotufolastat include positron emission tomogram abnormal, drug effect less than expected, and no adverse event, based on 111 FDA adverse event reports from 2004 to 2025.

Flotufolastat side effects

Percentages show how often each reaction appears relative to total reports for flotufolastat.

1
Positron Emission Tomogram Abnormal8.1%9
2
Drug Effect Less Than Expected7.2%8
3
No Adverse Event7.2%8
4
Dyspnoea3.6%4
5
Toxic Skin Eruption2.7%3
6
Pneumonia2.7%3
7
White Blood Cell Count Decreased2.7%3
8
Pyrexia2.7%3
9
Interstitial Lung Disease2.7%3
10
Oedema Peripheral2.7%3
11
Cough2.7%3
12
Nausea2.7%3
13
Renal Failure2.7%3
14
Death2.7%3
15
Accidental Exposure To Product2.7%3

These are voluntary reports and do not establish that flotufolastat caused these reactions.

Report severity

66.7%Serious74 reports
40.5%Hospitalizations45 reports
8.1%Fatal9 reports

Seriousness is determined by the reporter, not by OpenClaim.

Flotufolastat drug interactions

Other drugs that appear in adverse event reports alongside flotufolastat. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Terbinafine9.9%11
2
Nivolumab3.6%4
3
Relugolix3.6%4
4
Docetaxel2.7%3
5
Itraconazole1.8%2
6
Telmisartan1.8%2
7
Valsartan1.8%2
8
Nifedipine1.8%2
9
Paclitaxel1.8%2
10
Carboplatin1.8%2
11
Trastuzumab1.8%2
12
Sorafenib-tosylate1.8%2
13
Darbepoetin-alfa1.8%2
14
Pregabalin1.8%2
15
Esomeprazole1.8%2

Taken alongside

1
Amlodipine13.5%15
2
Aspirin12.6%14
3
Atorvastatin-calcium9.0%10
4
Furosemide8.1%9
5
Insulin7.2%8
6
Acetaminophen7.2%8
7
Cetirizine-hydrochloride6.3%7
8
Levofloxacin5.4%6
9
Telmisartan5.4%6
10
Prednisolone5.4%6
11
Pioglitazone-hydrochloride4.5%5
12
Famotidine4.5%5
13
Zolpidem-tartrate4.5%5
14
Lisinopril4.5%5
15
Oxycodone4.5%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports flotufolastat side effects

33.3% of flotufolastat adverse event reports involve female patients and 59.5% involve male patients. The largest age group is elderly at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female33.3%
Male59.5%
Unknown7.2%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6445.5%
65+54.5%

What is flotufolastat used for

Conditions and purposes for which patients were taking flotufolastat when the adverse event was reported.

Antifungal TreatmentAdenocarcinoma GastricDry SkinDiagnostic ProcedureFibromaFungal ParonychiaHer2 Positive Gastric CancerHerpes ZosterNail TineaOnychomycosisOral CandidiasisProduct Used For Unknown IndicationProphylaxisPositron Emission TomogramPositron Emission Tomogram Prostate

Showing 15 of 20 indications

Flotufolastat brand names and reporting trend

Flotufolastat is sold under the brand name Posluma.

Brand names

Posluma89

Quarterly reports (20042025)

200520102025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking flotufolastat with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.