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Florbetapir Side Effects

The most commonly reported side effects of florbetapir include amyloid related imaging abnormality-oedema/effusion, amyloid related imaging abnormality-microhaemorrhages and haemosiderin deposits, and headache, based on 117 FDA adverse event reports from 2013 to 2025. 2.6% of reports found the drug to be ineffective.

Florbetapir side effects

Percentages show how often each reaction appears relative to total reports for florbetapir.

1
Amyloid Related Imaging Abnormality-oedema/effusion24.8%29
2
Amyloid Related Imaging Abnormality-microhaemorrhages And Haemosiderin Deposits23.9%28
3
Headache12.8%15
4
Superficial Siderosis Of Central Nervous System7.7%9
5
Injection Site Pain6.0%7
6
Nausea5.1%6
7
Vomiting4.3%5
8
Fatigue3.4%4
9
Pain In Extremity3.4%4
10
Chest Pain3.4%4
11
Seizure3.4%4
12
Drug Ineffective2.6%3
13
Fall2.6%3
14
Burning Sensation2.6%3
15
Migraine2.6%3

These are voluntary reports and do not establish that florbetapir caused these reactions.

Report severity

23.1%Serious27 reports
13.7%Hospitalizations16 reports
0.9%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Florbetapir drug interactions

Other drugs that appear in adverse event reports alongside florbetapir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aducanumab-avwa39.3%46
2
Sodium-oxybate2.6%3
3
Flortaucipir-f-181.7%2
4
Galcanezumab-gnlm1.7%2
5
Exenatide-synthetic0.9%1
6
Olanzapine0.9%1
7
Tadalafil0.9%1
8
Zolpidem-tartrate0.9%1
9
Escitalopram-oxalate0.9%1
10
Trazodone-hydrochloride0.9%1
11
Clonazepam0.9%1
12
Triamcinolone0.9%1
13
Promethazine-hydrochloride0.9%1
14
Metoclopramide-hydrochloride0.9%1
15
Duloxetine-hydrochloride0.9%1

Taken alongside

1
Donepezil-hydrochloride18.8%22
2
Ergocalciferol16.2%19
3
Aspirin14.5%17
4
Atorvastatin-calcium10.3%12
5
Acetaminophen10.3%12
6
Metformin7.7%9
7
Cyanocobalamin7.7%9
8
Memantine-hydrochloride7.7%9
9
Rosuvastatin6.8%8
10
Levothyroxine-sodium6.8%8
11
Fluticasone6.8%8
12
Lisinopril6.0%7
13
Amlodipine6.0%7
14
Ascorbic-acid6.0%7
15
Simvastatin6.0%7

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports florbetapir side effects

47.0% of florbetapir adverse event reports involve female patients and 33.3% involve male patients. The largest age group is elderly at 82%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.0%
Male33.3%
Unknown19.7%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6417.9%
65+82.1%

What is florbetapir used for

Conditions and purposes for which patients were taking florbetapir when the adverse event was reported.

AmyloidosisAphasiaCognitive DisorderDementiaDementia Alzheimer^s TypeDiagnostic ProcedureDementia Alzheimer^s TypeMemory ImpairmentNeuritic PlaquesPositron Emission TomogramProduct Used For Unknown IndicationPositron Emission TomogramProduct Used For Unknown IndicationRadioisotope ScanScan

Showing 15 of 17 indications

Florbetapir brand names and reporting trend

Florbetapir is sold under the brand name Amyvid.

Brand names

Amyvid7

Quarterly reports (20132025)

201320162025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking florbetapir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.