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Fitusiran Side Effects

The most commonly reported side effects of fitusiran include chest pain, haemorrhage, and off label use, based on 12 FDA adverse event reports from 2025 to 2025.

Fitusiran side effects

Percentages show how often each reaction appears relative to total reports for fitusiran.

1
Chest Pain25.0%3
2
Haemorrhage25.0%3
3
Off Label Use16.7%2
4
Abdominal Pain Lower16.7%2
5
Arthralgia16.7%2
6
Fall8.3%1
7
Abdominal Distension8.3%1
8
Limb Injury8.3%1
9
Contusion8.3%1
10
Peripheral Swelling8.3%1
11
Antithrombin Iii Deficiency8.3%1
12
Cholecystitis8.3%1
13
Abdominal Pain Upper8.3%1
14
Nausea8.3%1
15
Vomiting8.3%1

These are voluntary reports and do not establish that fitusiran caused these reactions.

Report severity

41.7%Serious5 reports
33.3%Hospitalizations4 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Who reports fitusiran side effects

16.7% of fitusiran adverse event reports involve female patients and 83.3% involve male patients. The largest age group is adult at 78%. These figures reflect who reports side effects, not underlying risk.

Sex

Female16.7%
Male83.3%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–1722.2%
18–6477.8%
65+0.0%

What is fitusiran used for

Conditions and purposes for which patients were taking fitusiran when the adverse event was reported.

Factor Ix DeficiencyFactor Vii DeficiencyFactor Viii DeficiencyHaemophiliaProphylaxis

Fitusiran brand names and reporting trend

Fitusiran is sold under the brand name Qfitlia.

Brand names

Qfitlia5

Quarterly reports (20252025)

20252025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking fitusiran with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.