OpenClaim

Fezolinetant Side Effects

The most commonly reported side effects of fezolinetant include alanine aminotransferase increased, hepatic enzyme increased, and aspartate aminotransferase increased, based on 1,719 FDA adverse event reports from 2023 to 2025. 12.4% of reports found the drug to be ineffective.

Fezolinetant side effects

Percentages show how often each reaction appears relative to total reports for fezolinetant.

1
Drug Ineffective12.4%213
2
Alanine Aminotransferase Increased9.6%165
3
Hepatic Enzyme Increased8.4%145
4
Aspartate Aminotransferase Increased7.3%125
5
Off Label Use6.0%103
6
Headache5.5%95
7
Hot Flush5.0%86
8
Nausea4.9%84
9
Insomnia4.8%82
10
Liver Function Test Increased4.5%77
11
Diarrhoea3.9%67
12
Fatigue3.3%57
13
Abdominal Pain3.1%54
14
Dizziness3.1%54
15
Abdominal Pain Upper2.3%40

These are voluntary reports and do not establish that fezolinetant caused these reactions.

Report severity

17.6%Serious302 reports
3.0%Hospitalizations51 reports
0.1%Fatal2 reports

Seriousness is determined by the reporter, not by OpenClaim.

Fezolinetant drug interactions

Other drugs that appear in adverse event reports alongside fezolinetant. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Dupilumab1.3%23
2
Prednisone0.7%12
3
Avapritinib0.6%10
4
Gabapentin0.5%8
5
Metoprolol0.5%8
6
Rosuvastatin0.5%8
7
Sodium-oxybate0.4%7
8
Elacestrant-hydrochloride0.4%7
9
Suvorexant0.4%7
10
Doxepin-hydrochloride0.4%7
11
Fentanyl0.4%7
12
Hydromorphone-hydrochloride0.4%7
13
Duloxetine-hydrochloride0.4%7
14
Lorazepam0.4%7
15
Methylprednisolone0.4%7

Taken alongside

1
Levothyroxine-sodium3.4%59
2
Ergocalciferol3.3%57
3
Gabapentin2.9%49
4
Acetaminophen2.4%41
5
Atorvastatin-calcium2.2%37
6
Montelukast-sodium2.2%37
7
Pantoprazole-sodium2.0%34
8
Ondansetron1.9%32
9
Omeprazole1.8%31
10
Albuterol1.7%30
11
Estradiol1.7%30
12
Fluticasone1.7%29
13
Famotidine1.6%27
14
Metformin1.5%26
15
Amlodipine1.5%25

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports fezolinetant side effects

93.7% of fezolinetant adverse event reports involve female patients and 1.2% involve male patients. The largest age group is adult at 80%. These figures reflect who reports side effects, not underlying risk.

Sex

Female93.7%
Male1.2%
Unknown5.1%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6480.2%
65+19.8%

What is fezolinetant used for

Conditions and purposes for which patients were taking fezolinetant when the adverse event was reported.

Artificial MenopauseAutonomic Nervous System ImbalanceAutonomic NeuropathyBipolar Ii DisorderBreast CancerBreast Cancer MetastaticBreast TendernessChemotherapyCirculatory CollapseCoagulopathyFlushingGraves^ DiseaseGynaecological ExaminationHaemorrhageHeadache

Showing 15 of 31 indications

Fezolinetant brand names and reporting trend

Fezolinetant is sold under the brand name Veozah.

Brand names

Veozah234

Quarterly reports (20232025)

202320242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking fezolinetant with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.