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Ferumoxsil Side Effects

The most commonly reported side effects of ferumoxsil include anaemia, hepatic function abnormal, and interstitial lung disease, based on 481 FDA adverse event reports from 2004 to 2025.

Ferumoxsil side effects

Percentages show how often each reaction appears relative to total reports for ferumoxsil.

1
Anaemia5.8%28
2
Hepatic Function Abnormal5.6%27
3
Interstitial Lung Disease5.0%24
4
Platelet Count Decreased4.6%22
5
Anaemia4.4%21
6
Pyrexia4.0%19
7
Pyrexia4.0%19
8
Liver Disorder3.5%17
9
Malaise3.5%17
10
Decreased Appetite3.3%16
11
Aspartate Aminotransferase Increased3.1%15
12
Alanine Aminotransferase Increased2.9%14
13
Diarrhoea2.9%14
14
Decreased Appetite2.9%14
15
Pneumonia2.7%13

These are voluntary reports and do not establish that ferumoxsil caused these reactions.

Report severity

98.5%Serious474 reports
64.4%Hospitalizations310 reports
22.2%Fatal107 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ferumoxsil drug interactions

Other drugs that appear in adverse event reports alongside ferumoxsil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Infliximab4.6%22
2
Sorafenib-tosylate4.6%22
3
Ribavirin4.4%21
4
Peginterferon3.7%18
5
Prednisolone3.5%17
6
Methotrexate2.7%13
7
Prednisone2.7%13
8
Valsartan2.5%12
9
Aspirin2.5%12
10
Warfarin2.3%11
11
Etanercept2.3%11
12
Gemcitabine1.9%9
13
Furosemide1.9%9
14
Tacrolimus1.9%9
15
Famotidine1.7%8

Taken alongside

1
Furosemide17.0%82
2
Amlodipine15.2%73
3
Aspirin11.4%55
4
Prednisone9.4%45
5
Prednisolone7.5%36
6
Lansoprazole7.5%36
7
Diclofenac6.9%33
8
Magnesium-oxide6.4%31
9
Famotidine6.0%29
10
Esomeprazole6.0%29
11
Spironolactone5.4%26
12
Atorvastatin-calcium5.0%24
13
Taurursodiol4.8%23
14
Nifedipine4.6%22
15
Ursodiol4.4%21

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ferumoxsil side effects

44.7% of ferumoxsil adverse event reports involve female patients and 52.6% involve male patients. The largest age group is elderly at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.7%
Male52.6%
Unknown2.7%

Age group

< 20.0%
2–110.0%
12–170.5%
18–6433.6%
65+65.9%

What is ferumoxsil used for

Conditions and purposes for which patients were taking ferumoxsil when the adverse event was reported.

Abdominal DiscomfortAbdominal SymptomAdverse EventAortic Valve StenosisBlood Pressure AbnormalCholangiogramChronic GastritisColitis UlcerativeConstipationCrohn's DiseaseCrohn^s DiseaseDecreased AppetiteDepressionDrug Use For Unknown IndicationDuodenal Ulcer

Showing 15 of 44 indications

Ferumoxsil brand names and reporting trend

Ferumoxsil is sold under the brand name Gastromark.

Brand names

Gastromark2

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ferumoxsil with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.