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Ferric Pyrophosphate Citrate Side Effects

The most commonly reported side effects of ferric pyrophosphate citrate include thrombosis in device, fatigue, and dialysis, based on 416 FDA adverse event reports from 2004 to 2025. 4.6% of reports found the drug to be ineffective.

Ferric Pyrophosphate Citrate side effects

Percentages show how often each reaction appears relative to total reports for ferric pyrophosphate citrate.

1
Thrombosis In Device19.0%79
2
Drug Ineffective4.6%19
3
Fatigue4.6%19
4
Dialysis4.6%19
5
Nausea4.1%17
6
Pyrexia4.1%17
7
Malaise3.6%15
8
Off Label Use3.4%14
9
Diarrhoea3.4%14
10
Headache2.9%12
11
Asthma2.6%11
12
Vomiting2.6%11
13
Arthralgia2.6%11
14
Pain2.6%11
15
Pneumonia2.6%11

These are voluntary reports and do not establish that ferric pyrophosphate citrate caused these reactions.

Report severity

77.9%Serious324 reports
36.8%Hospitalizations153 reports
7.5%Fatal31 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ferric Pyrophosphate Citrate drug interactions

Other drugs that appear in adverse event reports alongside ferric pyrophosphate citrate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Palivizumab10.6%44
2
Sodium-chloride7.9%33
3
Prednisone2.2%9
4
Sirolimus2.2%9
5
Aspirin1.9%8
6
Methoxsalen1.9%8
7
Piperacillin1.9%8
8
Tazobactam-sodium1.9%8
9
Heparin1.7%7
10
Lumasiran-sodium1.7%7
11
Adalimumab1.4%6
12
Epoprostenol-sodium1.4%6
13
Prednisolone1.4%6
14
Tocilizumab1.4%6
15
Lenalidomide1.4%6

Taken alongside

1
Furosemide12.0%50
2
Ergocalciferol11.8%49
3
Acetaminophen9.1%38
4
Spironolactone8.2%34
5
Levothyroxine-sodium7.2%30
6
Amlodipine7.0%29
7
Calcium6.7%28
8
Atorvastatin-calcium6.3%26
9
Aspirin6.0%25
10
Omeprazole5.0%21
11
Famotidine4.8%20
12
Pantoprazole-sodium4.6%19
13
Albuterol4.1%17
14
Hydrochlorothiazide3.8%16
15
Cyanocobalamin3.8%16

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ferric pyrophosphate citrate side effects

45.0% of ferric pyrophosphate citrate adverse event reports involve female patients and 41.8% involve male patients. The largest age group is adult at 39%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.0%
Male41.8%
Unknown13.2%

Age group

< 221.5%
2–115.7%
12–172.2%
18–6438.8%
65+31.9%

What is ferric pyrophosphate citrate used for

Conditions and purposes for which patients were taking ferric pyrophosphate citrate when the adverse event was reported.

AnaemiaAnaemia NeonatalAnticoagulant TherapyApheresisAnaemiaAnaemia NeonatalAnticoagulant TherapyBlood Iron AbnormalBlood Iron DecreasedBone DisorderConstipationContinuous HaemodiafiltrationCrohn^s DiseaseDevice PrimingDialysis

Showing 15 of 53 indications

Ferric Pyrophosphate Citrate brand names and reporting trend

Ferric Pyrophosphate Citrate is sold under the brand name Triferic Avnu.

Brand names

Triferic Avnu362

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ferric pyrophosphate citrate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.