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Fenofibric Side Effects

The most commonly reported side effects of fenofibric include fatigue, nausea, and diarrhoea, based on 918 FDA adverse event reports from 2007 to 2025. 6.2% of reports found the drug to be ineffective.

Fenofibric side effects

Percentages show how often each reaction appears relative to total reports for fenofibric.

1
Fatigue7.2%66
2
Nausea6.3%58
3
Drug Ineffective6.2%57
4
Diarrhoea6.0%55
5
Pain5.1%47
6
Dizziness3.9%36
7
Asthenia3.6%33
8
Headache3.6%33
9
Arthralgia3.5%32
10
Dyspnoea3.3%30
11
Renal Failure3.3%30
12
Decreased Appetite2.9%27
13
Chronic Kidney Disease2.9%27
14
Myalgia2.8%26
15
Back Pain2.7%25

These are voluntary reports and do not establish that fenofibric caused these reactions.

Report severity

57.7%Serious530 reports
27.8%Hospitalizations255 reports
8.4%Fatal77 reports

Seriousness is determined by the reporter, not by OpenClaim.

Fenofibric drug interactions

Other drugs that appear in adverse event reports alongside fenofibric. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Atorvastatin-calcium4.9%45
2
Lenalidomide4.9%45
3
Adalimumab4.6%42
4
Omeprazole3.7%34
5
Apremilast3.7%34
6
Etanercept2.9%27
7
Metformin2.8%26
8
Sildenafil-citrate2.7%25
9
Alirocumab2.4%22
10
Dupilumab2.4%22
11
Insulin2.3%21
12
Esomeprazole2.1%19
13
Rosuvastatin2.0%18
14
Pantoprazole-sodium1.9%17
15
Pregabalin1.7%16

Taken alongside

1
Aspirin27.2%250
2
Ergocalciferol21.9%201
3
Metformin21.6%198
4
Atorvastatin-calcium19.9%183
5
Metoprolol18.7%172
6
Insulin17.6%162
7
Levothyroxine-sodium17.4%160
8
Omeprazole16.7%153
9
Lisinopril16.6%152
10
Rosuvastatin16.4%151
11
Acetaminophen15.5%142
12
Amlodipine15.3%140
13
Gabapentin13.5%124
14
Furosemide12.5%115
15
Losartan-potassium11.3%104

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports fenofibric side effects

43.7% of fenofibric adverse event reports involve female patients and 49.2% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.7%
Male49.2%
Unknown7.1%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6451.5%
65+48.5%

What is fenofibric used for

Conditions and purposes for which patients were taking fenofibric when the adverse event was reported.

Atrial FibrillationBlood CholesterolBlood Cholesterol AbnormalBlood Cholesterol IncreasedBlood Pressure MeasurementBlood TriglyceridesBlood Triglycerides AbnormalBlood Triglycerides IncreasedBreast CancerBreast Cancer FemaleBreast NeoplasmBlood CholesterolBlood Cholesterol AbnormalBlood Cholesterol IncreasedBlood Triglycerides

Showing 15 of 43 indications

Fenofibric brand names and reporting trend

Fenofibric is sold under the brand name Fibricor.

Brand names

Fibricor955

Quarterly reports (20072025)

2010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking fenofibric with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.