OpenClaim

Felodipine Side Effects

The most commonly reported side effects of felodipine include fatigue, dyspnoea, and diarrhoea, based on 13,794 FDA adverse event reports from 2004 to 2025.

Felodipine side effects

Percentages show how often each reaction appears relative to total reports for felodipine.

1
Fatigue7.4%1,018
2
Dyspnoea6.0%831
3
Diarrhoea5.8%806
4
Dizziness5.8%801
5
Headache5.6%769
6
Nausea5.5%760
7
Pain5.3%731
8
Pyrexia5.0%689
9
Off Label Use4.8%668
10
Malaise4.6%637
11
Arthralgia4.6%629
12
Vomiting4.5%627
13
Palpitations4.4%602
14
Abdominal Discomfort4.2%582
15
Pruritus4.2%577

These are voluntary reports and do not establish that felodipine caused these reactions.

Report severity

85.8%Serious11,838 reports
45.0%Hospitalizations6,204 reports
8.0%Fatal1,103 reports

Seriousness is determined by the reporter, not by OpenClaim.

Felodipine drug interactions

Other drugs that appear in adverse event reports alongside felodipine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Omeprazole5.4%743
2
Simvastatin4.8%659
3
Candesartan-cilexetil4.3%591
4
Levothyroxine-sodium4.2%576
5
Hydrochlorothiazide4.1%562
6
Lansoprazole3.9%533
7
Dapagliflozin3.8%527
8
Apixaban3.6%493
9
Bisoprolol-fumarate3.4%468
10
Naproxen3.3%452
11
Metformin3.2%445
12
Digoxin3.1%421
13
Adalimumab3.0%418
14
Aspirin3.0%408
15
Isosorbide2.8%390

Taken alongside

1
Aspirin21.6%2,977
2
Simvastatin16.5%2,277
3
Omeprazole15.7%2,168
4
Atorvastatin-calcium14.6%2,017
5
Acetaminophen14.0%1,938
6
Metoprolol12.0%1,660
7
Levothyroxine-sodium11.8%1,632
8
Furosemide11.7%1,614
9
Hydrochlorothiazide11.1%1,528
10
Metformin10.4%1,439
11
Bisoprolol-fumarate9.3%1,283
12
Lisinopril9.2%1,265
13
Losartan-potassium9.0%1,244
14
Atenolol8.3%1,141
15
Ramipril7.9%1,095

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports felodipine side effects

47.1% of felodipine adverse event reports involve female patients and 46.7% involve male patients. The largest age group is elderly at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.1%
Male46.7%
Unknown6.2%

Age group

< 20.1%
2–11<0.1%
12–170.1%
18–6434.3%
65+65.5%

What is felodipine used for

Conditions and purposes for which patients were taking felodipine when the adverse event was reported.

Acute Coronary SyndromeAngina PectorisAngina UnstableAnxietyAnxiety DisorderArrhythmiaArterial Occlusive DiseaseArthritisAtrial FibrillationAdverse Drug ReactionAngina PectorisAortic Valve ReplacementAtrial FibrillationBack PainBenign Prostatic Hyperplasia

Showing 15 of 160 indications

Felodipine brand names and reporting trend

Felodipine is sold under the brand name Lexxel.

Brand names

Lexxel12,374

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking felodipine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.