OpenClaim

Faricimab Side Effects

The most commonly reported side effects of faricimab include off label use, no adverse event, and visual impairment, based on 6,521 FDA adverse event reports from 2019 to 2025. 5.0% of reports found the drug to be ineffective.

Faricimab side effects

Percentages show how often each reaction appears relative to total reports for faricimab.

1
Off Label Use34.9%2,278
2
No Adverse Event29.2%1,902
3
Visual Impairment7.4%480
4
Drug Ineffective5.0%325
5
Death4.8%310
6
Uveitis4.7%309
7
Eye Inflammation4.7%307
8
Retinal Thickening4.6%299
9
Endophthalmitis3.7%239
10
Blindness3.5%225
11
Vitritis3.3%218
12
Vitreous Floaters3.3%215
13
Vision Blurred3.1%201
14
Iridocyclitis3.0%194
15
Optical Coherence Tomography Abnormal2.7%175

These are voluntary reports and do not establish that faricimab caused these reactions.

Report severity

40.8%Serious2,659 reports
6.2%Hospitalizations406 reports
5.4%Fatal349 reports

Seriousness is determined by the reporter, not by OpenClaim.

Faricimab drug interactions

Other drugs that appear in adverse event reports alongside faricimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bevacizumab6.7%439
2
Ranibizumab5.2%339
3
Aflibercept2.6%167
4
Dexamethasone0.2%14
5
Pegcetacoplan0.2%13
6
Brolucizumab-dbll0.2%10
7
Diazepam0.2%10
8
Treprostinil0.1%9
9
Dupilumab0.1%8
10
Aspirin0.1%7
11
Avacincaptad-pegol-sodium0.1%7
12
Mycophenolate<0.1%6
13
Fluoxetine-hydrochloride<0.1%6
14
Pembrolizumab<0.1%6
15
Rituximab<0.1%5

Taken alongside

1
Aflibercept5.5%359
2
Atorvastatin-calcium3.1%202
3
Aspirin2.9%189
4
Amlodipine2.4%155
5
Metformin2.3%147
6
Metoprolol1.9%122
7
Lisinopril1.9%121
8
Levothyroxine-sodium1.7%111
9
Insulin1.6%104
10
Losartan-potassium1.4%91
11
Acetaminophen1.4%90
12
Ranibizumab1.3%84
13
Ergocalciferol1.2%80
14
Rosuvastatin1.2%75
15
Omeprazole1.1%74

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports faricimab side effects

40.9% of faricimab adverse event reports involve female patients and 35.2% involve male patients. The largest age group is elderly at 72%. These figures reflect who reports side effects, not underlying risk.

Sex

Female40.9%
Male35.2%
Unknown23.9%

Age group

< 20.2%
2–11<0.1%
12–17<0.1%
18–6427.3%
65+72.4%

What is faricimab used for

Conditions and purposes for which patients were taking faricimab when the adverse event was reported.

Adverse EventAge-related Macular DegenerationAntiangiogenic TherapyBasal Cell Naevus SyndromeBorderline GlaucomaBreast Cancer FemaleCataractCataract NuclearCentral Serous ChorioretinopathyCerebral InfarctionCerebrovascular AccidentChorioretinal DisorderChorioretinal ScarChoroidal DystrophyChoroidal Neovascularisation

Showing 15 of 131 indications

Faricimab brand names and reporting trend

Faricimab is sold under the brand name Vabysmo.

Brand names

Vabysmo571

Quarterly reports (20192025)

2019202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking faricimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.