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Etretinate Side Effects

The most commonly reported side effects of etretinate include renal impairment, psoriasis, and pyrexia, based on 196 FDA adverse event reports from 2004 to 2025. 4.1% of reports found the drug to be ineffective.

Etretinate side effects

Percentages show how often each reaction appears relative to total reports for etretinate.

1
Renal Impairment6.6%13
2
Psoriasis6.6%13
3
Pyrexia5.6%11
4
Pneumonia5.6%11
5
Pruritus5.6%11
6
Pustular Psoriasis5.1%10
7
Erythema4.6%9
8
Interstitial Lung Disease4.6%9
9
Pyrexia4.1%8
10
Drug Ineffective4.1%8
11
Breast Cancer4.1%8
12
Diarrhoea3.6%7
13
Arthralgia3.6%7
14
Psoriasis3.1%6
15
Condition Aggravated3.1%6

These are voluntary reports and do not establish that etretinate caused these reactions.

Report severity

90.8%Serious178 reports
41.8%Hospitalizations82 reports
10.2%Fatal20 reports

Seriousness is determined by the reporter, not by OpenClaim.

Etretinate drug interactions

Other drugs that appear in adverse event reports alongside etretinate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cyclosporine20.9%41
2
Methotrexate15.3%30
3
Infliximab11.2%22
4
Secukinumab11.2%22
5
Adalimumab10.7%21
6
Ustekinumab7.7%15
7
Betamethasone4.6%9
8
Prednisolone4.6%9
9
Apremilast4.6%9
10
Guselkumab4.1%8
11
Risankizumab-rzaa2.6%5
12
Acitretin2.0%4
13
Clobetasol-propionate2.0%4
14
Prednisone2.0%4
15
Bexarotene2.0%4

Taken alongside

1
Prednisolone10.7%21
2
Betamethasone10.2%20
3
Cyclosporine9.2%18
4
Furosemide8.2%16
5
Ergocalciferol7.7%15
6
Hydrocortisone7.7%15
7
Methotrexate7.1%14
8
Amlodipine7.1%14
9
Acetaminophen7.1%14
10
Atorvastatin-calcium5.6%11
11
Levothyroxine-sodium5.6%11
12
Telmisartan5.1%10
13
Methylprednisolone4.6%9
14
Clindamycin4.6%9
15
Adalimumab4.6%9

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports etretinate side effects

45.9% of etretinate adverse event reports involve female patients and 49.5% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.9%
Male49.5%
Unknown4.6%

Age group

< 20.0%
2–110.6%
12–171.2%
18–6450.9%
65+47.3%

What is etretinate used for

Conditions and purposes for which patients were taking etretinate when the adverse event was reported.

Adult T-cell Lymphoma/leukaemiaAdult T-cell Lymphoma/leukaemia RefractoryAdverse EventAcne ConglobataBenign Familial PemphigusChronic Graft Versus Host DiseaseCutaneous T-cell Lymphoma Stage IvDermatitis PsoriasiformErythrodermic PsoriasisGeneralised Pustular PsoriasisJaundiceMuscle AtrophyNauseaNetherton^s SyndromePalmoplantar Pustulosis

Showing 15 of 30 indications

Etretinate brand names and reporting trend

Etretinate is sold under the brand name Tegison.

Brand names

Tegison211

Quarterly reports (20042025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking etretinate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.