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Etravirine Side Effects

The most commonly reported side effects of etravirine include pain, drug resistance, and anxiety, based on 4,448 FDA adverse event reports from 2006 to 2025. 3.2% of reports found the drug to be ineffective.

Etravirine side effects

Percentages show how often each reaction appears relative to total reports for etravirine.

1
Pain6.2%274
2
Drug Resistance5.7%255
3
Anxiety5.4%242
4
Emotional Distress5.4%242
5
Drug Interaction5.4%238
6
Virologic Failure5.1%226
7
Anhedonia4.9%219
8
Treatment Failure4.6%203
9
Death4.4%195
10
Chronic Kidney Disease4.4%194
11
Foetal Exposure During Pregnancy3.6%158
12
Viral Mutation Identified3.4%153
13
Renal Failure3.4%151
14
Lipodystrophy Acquired3.3%148
15
Anaemia3.3%145

These are voluntary reports and do not establish that etravirine caused these reactions.

Report severity

88.0%Serious3,914 reports
29.1%Hospitalizations1,293 reports
10.8%Fatal482 reports

Seriousness is determined by the reporter, not by OpenClaim.

Etravirine drug interactions

Other drugs that appear in adverse event reports alongside etravirine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ritonavir35.8%1,594
2
Darunavir35.6%1,585
3
Raltegravir-potassium35.0%1,557
4
Tenofovir31.7%1,409
5
Emtricitabine22.1%985
6
Lamivudine18.8%835
7
Zidovudine12.5%557
8
Abacavir12.3%549
9
Efavirenz9.1%403
10
Lopinavir8.3%369
11
Dolutegravir7.7%343
12
Didanosine6.4%283
13
Maraviroc6.1%270
14
Stavudine6.0%266
15
Nevirapine5.7%253

Taken alongside

1
Raltegravir-potassium21.0%936
2
Ritonavir19.3%859
3
Darunavir17.5%780
4
Tenofovir15.4%683
5
Emtricitabine13.0%580
6
Lamivudine10.9%487
7
Abacavir7.2%319
8
Zidovudine6.0%269
9
Dolutegravir5.8%256
10
Sulfamethoxazole5.4%241
11
Trimethoprim4.8%212
12
Aspirin4.6%203
13
Atorvastatin-calcium4.5%200
14
Acyclovir4.4%197
15
Omeprazole4.3%193

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports etravirine side effects

24.6% of etravirine adverse event reports involve female patients and 57.8% involve male patients. The largest age group is adult at 85%. These figures reflect who reports side effects, not underlying risk.

Sex

Female24.6%
Male57.8%
Unknown17.6%

Age group

< 24.0%
2–110.4%
12–171.5%
18–6485.4%
65+8.7%

What is etravirine used for

Conditions and purposes for which patients were taking etravirine when the adverse event was reported.

Acquired Immunodeficiency SyndromeAcute Hiv InfectionAidsAntiretroviral TherapyAntiviral ProphylaxisAntiviral TreatmentAsymptomatic Hiv InfectionAntiretroviral TherapyAntiviral TreatmentBack PainBlood Hiv RnaChronic Hepatitis BChronic Kidney DiseaseCongenital Oculomotor ApraxiaChronic Hepatitis C

Showing 15 of 67 indications

Etravirine brand names and reporting trend

Etravirine is sold under the brand name Etravirine.

Brand names

Etravirine2,093

Quarterly reports (20062025)

20062010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking etravirine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.