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Ethinyl Side Effects

The most commonly reported side effects of ethinyl include pain, pulmonary embolism, and pain, based on 127,420 FDA adverse event reports from 2004 to 2025. 3.5% of reports found the drug to be ineffective.

Ethinyl side effects

Percentages show how often each reaction appears relative to total reports for ethinyl.

1
Pain7.8%9,927
2
Pulmonary Embolism6.3%8,027
3
Pain5.9%7,557
4
Pulmonary Embolism5.7%7,283
5
Injury5.7%7,200
6
Deep Vein Thrombosis5.3%6,731
7
Anxiety4.4%5,661
8
Deep Vein Thrombosis4.4%5,621
9
Injury4.1%5,251
10
Fatigue3.8%4,820
11
Metrorrhagia3.8%4,809
12
Nausea3.7%4,770
13
Off Label Use3.6%4,563
14
Headache3.6%4,529
15
Drug Ineffective3.5%4,437

These are voluntary reports and do not establish that ethinyl caused these reactions.

Report severity

58.6%Serious74,702 reports
29.8%Hospitalizations38,017 reports
2.9%Fatal3,742 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ethinyl drug interactions

Other drugs that appear in adverse event reports alongside ethinyl. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Drospirenone32.4%41,286
2
Etonogestrel15.4%19,598
3
Norelgestromin12.9%16,389
4
Norethindrone4.3%5,442
5
Levonorgestrel4.2%5,297
6
Adalimumab3.5%4,501
7
Ulipristal-acetate3.1%3,956
8
Sodium-oxybate3.0%3,773
9
Norgestimate2.7%3,471
10
Etanercept2.7%3,435
11
Acetaminophen2.6%3,343
12
Certolizumab-pegol2.5%3,192
13
Abatacept2.5%3,179
14
Methotrexate2.5%3,125
15
Infliximab2.4%3,076

Taken alongside

1
Acetaminophen10.3%13,177
2
Ibuprofen8.6%10,986
3
Norethindrone6.6%8,381
4
Levonorgestrel5.4%6,877
5
Albuterol5.0%6,325
6
Desogestrel4.8%6,058
7
Ergocalciferol4.7%5,990
8
Norgestimate4.5%5,776
9
Levothyroxine-sodium4.4%5,619
10
Pantoprazole-sodium4.0%5,059
11
Hydrocodone3.8%4,818
12
Cetirizine-hydrochloride3.8%4,794
13
Drospirenone3.5%4,505
14
Prednisone3.3%4,228
15
Fluticasone3.3%4,202

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ethinyl side effects

94.6% of ethinyl adverse event reports involve female patients and 1.7% involve male patients. The largest age group is adult at 92%. These figures reflect who reports side effects, not underlying risk.

Sex

Female94.6%
Male1.7%
Unknown3.7%

Age group

< 20.3%
2–110.2%
12–175.4%
18–6492.3%
65+1.8%

What is ethinyl used for

Conditions and purposes for which patients were taking ethinyl when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal PainAbdominal Pain LowerAbdominal Pain UpperAbdominal RigidityAbnormal BehaviourAbnormal Uterine BleedingAbnormal Withdrawal BleedingAbortionAccidental Drug Intake By ChildAccidental ExposureAccidental Exposure To ProductAccidental Exposure To Product By ChildAcne

Showing 15 of 960 indications

Ethinyl brand names and reporting trend

Ethinyl is sold under the brand name Nordette-21.

Brand names

Nordette-211,789

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ethinyl with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.