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Etelcalcetide Side Effects

The most commonly reported side effects of etelcalcetide include underdose, shunt stenosis, and nausea, based on 2,875 FDA adverse event reports from 2013 to 2025. 2.7% of reports found the drug to be ineffective.

Etelcalcetide side effects

Percentages show how often each reaction appears relative to total reports for etelcalcetide.

1
Underdose8.6%247
2
Shunt Stenosis7.1%204
3
Nausea6.6%191
4
Hypocalcaemia5.2%149
5
Product Storage Error5.2%149
6
Blood Parathyroid Hormone Increased5.0%145
7
Shunt Occlusion4.4%127
8
Blood Calcium Decreased4.3%124
9
Diarrhoea4.1%117
10
Vomiting3.7%107
11
Circumstance Or Information Capable Of Leading To Medication Error2.9%82
12
Death2.8%81
13
Drug Ineffective2.7%77
14
Fall2.6%75
15
Cardiac Failure2.3%66

These are voluntary reports and do not establish that etelcalcetide caused these reactions.

Report severity

48.8%Serious1,402 reports
28.5%Hospitalizations818 reports
11.6%Fatal333 reports

Seriousness is determined by the reporter, not by OpenClaim.

Etelcalcetide drug interactions

Other drugs that appear in adverse event reports alongside etelcalcetide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cinacalcet-hydrochloride10.3%296
2
Estropipate1.0%30
3
Denosumab0.9%26
4
Darbepoetin-alfa0.7%20
5
Levofloxacin0.6%17
6
Tenapanor-hydrochloride0.5%13
7
Ferric-oxyhydroxide0.4%11
8
Calcitriol0.3%10
9
Methoxy-polyethylene-glycol-epoetin-beta0.3%9
10
Warfarin0.3%8
11
Gemfibrozil0.2%7
12
Paricalcitol0.2%7
13
Aspirin0.2%6
14
Ferric-citrate0.2%6
15
Ipilimumab0.2%5

Taken alongside

1
Lanthanum-carbonate13.8%398
2
Darbepoetin-alfa12.5%360
3
Calcitriol9.2%265
4
Calcium-carbonate7.1%203
5
Ferric-citrate5.1%146
6
Sevelamer4.6%131
7
Epoetin3.2%93
8
Iron2.9%84
9
Methoxy-polyethylene-glycol-epoetin-beta2.7%78
10
Aspirin2.6%76
11
Paricalcitol2.6%74
12
Ferric-oxyhydroxide2.2%64
13
Amlodipine2.1%59
14
Carvedilol1.8%53
15
Calcium1.6%47

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports etelcalcetide side effects

34.5% of etelcalcetide adverse event reports involve female patients and 39.6% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.5%
Male39.6%
Unknown25.9%

Age group

< 2<0.1%
2–110.3%
12–170.0%
18–6451.0%
65+48.6%

What is etelcalcetide used for

Conditions and purposes for which patients were taking etelcalcetide when the adverse event was reported.

AnaemiaAdjusted Calcium IncreasedBlood Calcium IncreasedBlood Parathyroid Hormone AbnormalBlood Parathyroid Hormone IncreasedBlood Parathyroid Hormone AbnormalBlood Parathyroid Hormone IncreasedBone DisorderCalciphylaxisCalcium Metabolism DisorderChronic Kidney DiseaseChronic Kidney Disease-mineral And Bone DisorderChronic Kidney DiseaseChronic Kidney Disease-mineral And Bone DisorderCongenital Cystic Kidney Disease

Showing 15 of 51 indications

Etelcalcetide brand names and reporting trend

Etelcalcetide is sold under the brand name Parsabiv.

Brand names

Parsabiv1,517

Quarterly reports (20132025)

2013202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking etelcalcetide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.