The most commonly reported side effects of etanercept include pain, arthralgia, and rheumatoid arthritis, based on 598,499 FDA adverse event reports from 2004 to 2025. 12.0% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for etanercept.
These are voluntary reports and do not establish that etanercept caused these reactions.
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Other drugs that appear in adverse event reports alongside etanercept. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
68.9% of etanercept adverse event reports involve female patients and 23.5% involve male patients. The largest age group is adult at 72%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking etanercept when the adverse event was reported.
Showing 15 of 1,383 indications
Etanercept is sold under brand names including Enbrel, Erelzi.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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