OpenClaim

Eslicarbazepine Side Effects

The most commonly reported side effects of eslicarbazepine include seizure, off label use, and dizziness, based on 3,745 FDA adverse event reports from 2005 to 2025. 10.7% of reports found the drug to be ineffective.

Eslicarbazepine side effects

Percentages show how often each reaction appears relative to total reports for eslicarbazepine.

1
Seizure29.0%1,085
2
Drug Ineffective10.7%400
3
Off Label Use10.2%381
4
Dizziness6.9%257
5
Somnolence6.2%233
6
Hyponatraemia5.4%204
7
Fatigue4.7%175
8
Headache4.0%148
9
Fall3.7%138
10
Generalised Tonic-clonic Seizure3.6%133
11
Nausea3.3%125
12
Condition Aggravated3.3%124
13
Rash3.2%121
14
Memory Impairment3.1%117
15
Drug Interaction2.8%104

These are voluntary reports and do not establish that eslicarbazepine caused these reactions.

Report severity

71.5%Serious2,678 reports
23.7%Hospitalizations888 reports
3.3%Fatal125 reports

Seriousness is determined by the reporter, not by OpenClaim.

Eslicarbazepine drug interactions

Other drugs that appear in adverse event reports alongside eslicarbazepine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Levetiracetam14.9%559
2
Lacosamide10.7%401
3
Lamotrigine9.4%352
4
Brivaracetam7.1%267
5
Clobazam6.7%251
6
Perampanel5.7%215
7
Cenobamate5.4%201
8
Topiramate5.1%192
9
Zonisamide4.2%157
10
Phenytoin4.2%156
11
Cannabidiol4.1%155
12
Valproic-acid4.0%149
13
Phenobarbital-sodium3.7%137
14
Carbamazepine3.1%115
15
Valproate-sodium2.7%100

Taken alongside

1
Levetiracetam10.0%374
2
Lamotrigine6.3%237
3
Clobazam6.0%226
4
Lacosamide5.1%190
5
Clonazepam4.8%179
6
Topiramate4.6%173
7
Perampanel3.9%147
8
Levothyroxine-sodium3.5%130
9
Zonisamide3.5%130
10
Acetaminophen3.2%120
11
Lorazepam3.2%118
12
Pregabalin3.1%116
13
Brivaracetam3.1%115
14
Phenytoin2.9%107
15
Gabapentin2.8%104

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports eslicarbazepine side effects

41.1% of eslicarbazepine adverse event reports involve female patients and 31.2% involve male patients. The largest age group is adult at 75%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.1%
Male31.2%
Unknown27.6%

Age group

< 21.0%
2–114.8%
12–174.4%
18–6474.8%
65+15.0%

What is eslicarbazepine used for

Conditions and purposes for which patients were taking eslicarbazepine when the adverse event was reported.

AggressionAneurysmAuraAutism Spectrum DisorderAllergy TestAnaplastic AstrocytomaAntisocial Personality DisorderAphasiaAsthmaAstrocytomaAtypical Benign Partial EpilepsyBalance DisorderBenign NeoplasmBenign Rolandic EpilepsyBipolar Disorder

Showing 15 of 123 indications

Eslicarbazepine brand names and reporting trend

Eslicarbazepine is sold under the brand name Aptiom.

Brand names

Aptiom1,739

Quarterly reports (20052025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking eslicarbazepine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.