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Eribulin Side Effects

The most commonly reported side effects of eribulin include neutropenia, malignant neoplasm progression, and myelosuppression, based on 6,604 FDA adverse event reports from 2010 to 2025.

Eribulin side effects

Percentages show how often each reaction appears relative to total reports for eribulin.

1
Neutropenia12.5%824
2
Malignant Neoplasm Progression11.5%758
3
Myelosuppression8.6%568
4
Febrile Neutropenia7.7%507
5
Neuropathy Peripheral5.4%359
6
Disease Progression5.1%337
7
Pyrexia4.9%324
8
Neutrophil Count Decreased4.8%320
9
White Blood Cell Count Decreased4.7%310
10
Fatigue4.4%291
11
Nausea3.8%249
12
Metastases To Liver3.7%246
13
Anaemia3.4%227
14
Leukopenia3.4%225
15
Metastases To Bone3.3%219

These are voluntary reports and do not establish that eribulin caused these reactions.

Report severity

94.5%Serious6,244 reports
48.9%Hospitalizations3,230 reports
16.5%Fatal1,090 reports

Seriousness is determined by the reporter, not by OpenClaim.

Eribulin drug interactions

Other drugs that appear in adverse event reports alongside eribulin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Capecitabine16.6%1,093
2
Paclitaxel13.5%894
3
Trastuzumab11.4%756
4
Gemcitabine9.4%622
5
Vinorelbine-tartrate8.0%526
6
Carboplatin7.9%525
7
Docetaxel7.7%506
8
Fulvestrant7.5%495
9
Doxorubicin-hydrochloride6.3%414
10
Cyclophosphamide6.1%402
11
Palbociclib5.8%385
12
Letrozole5.7%378
13
Pertuzumab5.6%373
14
Everolimus5.5%364
15
Tamoxifen-citrate5.4%357

Taken alongside

1
Dexamethasone5.0%332
2
Paclitaxel4.5%294
3
Acetaminophen3.8%249
4
Ondansetron3.5%232
5
Capecitabine3.4%224
6
Oxycodone3.2%213
7
Zoledronic-acid3.2%213
8
Trastuzumab2.8%187
9
Omeprazole2.8%182
10
Furosemide2.6%173
11
Fulvestrant2.5%168
12
Docetaxel2.3%155
13
Vinorelbine-tartrate2.3%152
14
Denosumab2.3%150
15
Gemcitabine2.1%140

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports eribulin side effects

89.2% of eribulin adverse event reports involve female patients and 5.8% involve male patients. The largest age group is adult at 70%. These figures reflect who reports side effects, not underlying risk.

Sex

Female89.2%
Male5.8%
Unknown5.0%

Age group

< 20.0%
2–11<0.1%
12–170.3%
18–6469.8%
65+29.9%

What is eribulin used for

Conditions and purposes for which patients were taking eribulin when the adverse event was reported.

AdenocarcinomaAdenoid Cystic CarcinomaAdrenal Gland CancerAdrenal MassAngiosarcomaAngiosarcoma RecurrentApocrine Breast CarcinomaAdenoid Cystic CarcinomaAdrenal Gland CancerAngiosarcomaAngiosarcoma RecurrentBladder CancerBladder Transitional Cell CarcinomaBone Marrow DisorderBone Marrow Infiltration

Showing 15 of 295 indications

Eribulin brand names and reporting trend

Quarterly reports (20102025)

201020122016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking eribulin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.