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Ergocalciferol Side Effects

The most commonly reported side effects of ergocalciferol include fatigue, nausea, and diarrhoea, based on 438,351 FDA adverse event reports from 2004 to 2025. 6.3% of reports found the drug to be ineffective.

Ergocalciferol side effects

Percentages show how often each reaction appears relative to total reports for ergocalciferol.

1
Fatigue9.2%40,511
2
Nausea6.7%29,544
3
Diarrhoea6.5%28,543
4
Drug Ineffective6.3%27,450
5
Headache6.2%27,286
6
Off Label Use6.1%26,585
7
Pain5.8%25,470
8
Arthralgia4.8%21,137
9
Dyspnoea4.7%20,753
10
Dizziness4.6%20,366
11
Asthenia4.1%17,770
12
Fall4.0%17,490
13
Vomiting3.7%16,386
14
Pain In Extremity3.5%15,556
15
Malaise3.5%15,451

These are voluntary reports and do not establish that ergocalciferol caused these reactions.

Report severity

58.7%Serious257,332 reports
26.8%Hospitalizations117,281 reports
5.8%Fatal25,602 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ergocalciferol drug interactions

Other drugs that appear in adverse event reports alongside ergocalciferol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab6.3%27,703
2
Lenalidomide5.5%24,152
3
Etanercept3.2%14,033
4
Sodium-oxybate2.8%12,309
5
Prednisone2.5%11,146
6
Infliximab2.5%11,000
7
Methotrexate2.5%10,942
8
Denosumab2.3%10,175
9
Dupilumab2.2%9,529
10
Tofacitinib2.1%9,171
11
Dalfampridine2.0%8,734
12
Pantoprazole-sodium1.9%8,270
13
Rituximab1.9%8,266
14
Abatacept1.8%7,952
15
Acetaminophen1.8%7,859

Taken alongside

1
Aspirin21.4%93,606
2
Acetaminophen19.5%85,636
3
Calcium19.0%83,340
4
Levothyroxine-sodium17.1%75,086
5
Cyanocobalamin15.1%66,312
6
Omeprazole13.2%57,850
7
Ascorbic-acid12.7%55,541
8
Atorvastatin-calcium12.4%54,477
9
Gabapentin11.6%51,027
10
Albuterol11.5%50,591
11
Folic-acid10.7%46,857
12
Amlodipine10.5%46,024
13
Metoprolol10.5%45,832
14
Prednisone10.4%45,678
15
Furosemide10.2%44,538

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ergocalciferol side effects

66.4% of ergocalciferol adverse event reports involve female patients and 27.4% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female66.4%
Male27.4%
Unknown6.1%

Age group

< 20.5%
2–111.1%
12–171.5%
18–6451.9%
65+44.9%

What is ergocalciferol used for

Conditions and purposes for which patients were taking ergocalciferol when the adverse event was reported.

Abdominal DiscomfortAbnormal FaecesAcneAcquired PorokeratosisAcromegalyAcute Kidney InjuryAcute Myeloid LeukaemiaAdjuvant TherapyAdrenal InsufficiencyAdrenocortical Steroid TherapyAdverse Drug ReactionAdverse EventAffective DisorderAlagille SyndromeAlcoholism

Showing 15 of 1,338 indications

Ergocalciferol brand names and reporting trend

Ergocalciferol is sold under the brand name M.v.i.-12 Adult.

Brand names

M.v.i.-12 Adult34,835

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ergocalciferol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.