OpenClaim

Erenumab Side Effects

The most commonly reported side effects of erenumab include accidental exposure to product, device difficult to use, and wrong technique in product usage process, based on 54,268 FDA adverse event reports from 2009 to 2025. 8.1% of reports found the drug to be ineffective.

Erenumab side effects

Percentages show how often each reaction appears relative to total reports for erenumab.

1
Accidental Exposure To Product18.5%10,038
2
Device Difficult To Use18.0%9,770
3
Wrong Technique In Product Usage Process17.4%9,454
4
Drug Dose Omission By Device12.0%6,524
5
Migraine9.0%4,895
6
Drug Ineffective8.1%4,409
7
Headache6.2%3,340
8
Constipation6.0%3,261
9
Product Storage Error5.5%2,974
10
Injection Site Pain5.3%2,854
11
Off Label Use5.1%2,755
12
Nausea4.4%2,404
13
Fatigue4.2%2,270
14
Alopecia4.0%2,196
15
Therapeutic Product Effect Incomplete3.6%1,954

These are voluntary reports and do not establish that erenumab caused these reactions.

Report severity

21.5%Serious11,657 reports
7.8%Hospitalizations4,239 reports
4.8%Fatal2,603 reports

Seriousness is determined by the reporter, not by OpenClaim.

Erenumab drug interactions

Other drugs that appear in adverse event reports alongside erenumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Topiramate4.4%2,373
2
Candesartan-cilexetil4.1%2,231
3
Etanercept4.0%2,191
4
Diclofenac4.0%2,175
5
Adalimumab4.0%2,161
6
Secukinumab3.9%2,108
7
Leflunomide3.7%2,001
8
Rituximab3.7%1,992
9
Oxycodone3.6%1,943
10
Methotrexate3.4%1,835
11
Cetirizine-hydrochloride3.2%1,748
12
Naproxen3.2%1,740
13
Abatacept3.2%1,721
14
Lamotrigine3.2%1,720
15
Prednisone3.1%1,667

Taken alongside

1
Acetaminophen3.4%1,820
2
Topiramate2.9%1,582
3
Sumatriptan2.7%1,439
4
Ergocalciferol2.4%1,290
5
Onabotulinumtoxina2.3%1,248
6
Gabapentin1.7%908
7
Ibuprofen1.7%898
8
Naproxen1.6%884
9
Levothyroxine-sodium1.5%804
10
Pantoprazole-sodium1.4%750
11
Rizatriptan-benzoate1.3%727
12
Cyanocobalamin1.3%725
13
Amitriptyline-hydrochloride1.3%704
14
Calcium1.3%693
15
Caffeine1.3%692

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports erenumab side effects

70.3% of erenumab adverse event reports involve female patients and 11.5% involve male patients. The largest age group is adult at 82%. These figures reflect who reports side effects, not underlying risk.

Sex

Female70.3%
Male11.5%
Unknown18.2%

Age group

< 20.2%
2–11<0.1%
12–170.7%
18–6482.0%
65+17.0%

What is erenumab used for

Conditions and purposes for which patients were taking erenumab when the adverse event was reported.

Abdominal DistensionAbdominal MigraineAdrenal DisorderAneurysmAnkylosing SpondylitisAnxietyAphasiaArnold-chiari MalformationArthritisAsthmaAtaxiaAutoimmune ThyroiditisAutonomic Nervous System ImbalanceAbdominal MigraineAneurysm

Showing 15 of 226 indications

Erenumab brand names and reporting trend

Erenumab is sold under the brand name Aimovig.

Brand names

Aimovig3,179

Quarterly reports (20092025)

2009202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking erenumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.