OpenClaim

Ensartinib Side Effects

The most commonly reported side effects of ensartinib include rash, disease progression, and product use issue, based on 60 FDA adverse event reports from 2005 to 2025. 8.3% of reports found the drug to be ineffective.

Ensartinib side effects

Percentages show how often each reaction appears relative to total reports for ensartinib.

1
Drug Ineffective8.3%5
2
Rash8.3%5
3
Disease Progression6.7%4
4
Drug Ineffective5.0%3
5
Product Use Issue5.0%3
6
Pruritus5.0%3
7
Oedema5.0%3
8
Rheumatoid Arthritis3.3%2
9
Arthralgia3.3%2
10
Tubulointerstitial Nephritis3.3%2
11
Blood Creatine Phosphokinase Increased3.3%2
12
Drug Resistance3.3%2
13
Constipation3.3%2
14
Myocardial Necrosis Marker Increased3.3%2
15
Pleural Effusion3.3%2

These are voluntary reports and do not establish that ensartinib caused these reactions.

Report severity

91.7%Serious55 reports
48.3%Hospitalizations29 reports
8.3%Fatal5 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ensartinib drug interactions

Other drugs that appear in adverse event reports alongside ensartinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab26.7%16
2
Alectinib-hydrochloride23.3%14
3
Emtricitabine3.3%2
4
Tenofovir3.3%2
5
Ceritinib3.3%2
6
Crizotinib3.3%2
7
Bevacizumab3.3%2
8
Aspirin1.7%1
9
Dipyridamole1.7%1
10
Hydrocortisone1.7%1
11
Methotrexate1.7%1
12
Sulfasalazine1.7%1
13
Prednisone1.7%1
14
Amlodipine1.7%1
15
Hydrochlorothiazide1.7%1

Taken alongside

1
Methotrexate16.7%10
2
Folic-acid10.0%6
3
Prednisolone8.3%5
4
Cisplatin6.7%4
5
Crizotinib6.7%4
6
Lorlatinib6.7%4
7
Pantoprazole-sodium5.0%3
8
Leflunomide5.0%3
9
Omeprazole5.0%3
10
Calcium5.0%3
11
Methylprednisolone5.0%3
12
Moxifloxacin-hydrochloride5.0%3
13
Buprenorphine5.0%3
14
Brigatinib5.0%3
15
Aspirin3.3%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ensartinib side effects

48.3% of ensartinib adverse event reports involve female patients and 43.3% involve male patients. The largest age group is adult at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female48.3%
Male43.3%
Unknown8.3%

Age group

< 20.0%
2–112.2%
12–170.0%
18–6455.6%
65+42.2%

What is ensartinib used for

Conditions and purposes for which patients were taking ensartinib when the adverse event was reported.

Alk Gene Rearrangement PositiveAdenocarcinomaBlindnessDiffuse Large B-cell LymphomaFlank PainLung AdenocarcinomaLung Adenocarcinoma Stage IvLung Carcinoma Cell Type Unspecified RecurrentLung Neoplasm MalignantMetastases To Central Nervous SystemNeoplasmNon-small Cell Lung CancerProduct Used For Unknown IndicationProduct Used For Unknown IndicationRheumatoid Arthritis

Showing 15 of 17 indications

Ensartinib brand names and reporting trend

Ensartinib is sold under the brand name Ensacove.

Brand names

Ensacove70

Quarterly reports (20052025)

200520102025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ensartinib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.