OpenClaim

Enoxaparin Side Effects

The most commonly reported side effects of enoxaparin include off label use, dyspnoea, and nausea, based on 80,297 FDA adverse event reports from 2004 to 2025. 2.2% of reports found the drug to be ineffective.

Enoxaparin side effects

Percentages show how often each reaction appears relative to total reports for enoxaparin.

1
Off Label Use5.3%4,275
2
Dyspnoea3.4%2,757
3
Nausea3.3%2,683
4
Diarrhoea3.3%2,646
5
Acute Kidney Injury3.2%2,538
6
Pyrexia3.1%2,523
7
Fatigue3.0%2,417
8
Anaemia2.9%2,291
9
Vomiting2.6%2,082
10
Death2.5%1,992
11
Pneumonia2.4%1,960
12
Thrombocytopenia2.4%1,891
13
Drug Ineffective2.2%1,786
14
Pulmonary Embolism2.0%1,643
15
Fall1.9%1,562

These are voluntary reports and do not establish that enoxaparin caused these reactions.

Report severity

88.2%Serious70,785 reports
54.4%Hospitalizations43,686 reports
15.5%Fatal12,479 reports

Seriousness is determined by the reporter, not by OpenClaim.

Enoxaparin drug interactions

Other drugs that appear in adverse event reports alongside enoxaparin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide5.0%3,993
2
Aspirin4.8%3,894
3
Dexamethasone4.4%3,556
4
Warfarin3.8%3,023
5
Acetaminophen3.7%2,931
6
Heparin2.5%1,971
7
Pantoprazole-sodium2.4%1,948
8
Prednisone2.4%1,941
9
Cyclophosphamide2.3%1,871
10
Rivaroxaban2.3%1,856
11
Rituximab2.2%1,771
12
Furosemide2.2%1,749
13
Ceftriaxone-sodium2.1%1,706
14
Omeprazole2.1%1,702
15
Doxorubicin-hydrochloride2.1%1,689

Taken alongside

1
Acetaminophen19.8%15,924
2
Pantoprazole-sodium11.9%9,562
3
Furosemide11.8%9,460
4
Aspirin11.4%9,184
5
Ondansetron9.9%7,954
6
Omeprazole9.5%7,632
7
Dexamethasone9.0%7,247
8
Levothyroxine-sodium7.5%6,054
9
Oxycodone7.2%5,818
10
Atorvastatin-calcium6.9%5,517
11
Albuterol6.8%5,436
12
Metoprolol6.7%5,386
13
Amlodipine6.7%5,362
14
Insulin6.7%5,345
15
Acyclovir6.2%4,943

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports enoxaparin side effects

47.4% of enoxaparin adverse event reports involve female patients and 43.1% involve male patients. The largest age group is adult at 49%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.4%
Male43.1%
Unknown9.6%

Age group

< 21.7%
2–111.0%
12–171.2%
18–6448.5%
65+47.5%

What is enoxaparin used for

Conditions and purposes for which patients were taking enoxaparin when the adverse event was reported.

Abdominal DistensionAbdominal ExplorationAbdominal OperationAbdominal PainAbdominal Wall HaemorrhageAbdominoplastyAbnormal Clotting FactorAbortion SpontaneousAccidental ExposureAccidental Exposure To ProductActivated Protein C ResistanceAcute Coronary SyndromeAcute Kidney InjuryAcute Left Ventricular FailureAcute Myeloid Leukaemia

Showing 15 of 1,685 indications

Enoxaparin brand names and reporting trend

Enoxaparin is sold under the brand name Enoxaparin Sodium (preservative Free).

Brand names

Enoxaparin Sodium (preservative Free)54,204

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking enoxaparin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.