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Enflurane Side Effects

The most commonly reported side effects of enflurane include drug interaction, myocardial ischaemia, and post procedural complication, based on 97 FDA adverse event reports from 2004 to 2024.

Enflurane side effects

Percentages show how often each reaction appears relative to total reports for enflurane.

1
Drug Interaction18.6%18
2
Myocardial Ischaemia12.4%12
3
Post Procedural Complication11.3%11
4
Bradycardia9.3%9
5
Haemolysis7.2%7
6
Alkalosis6.2%6
7
Oculogyric Crisis6.2%6
8
Pyrexia5.2%5
9
Mydriasis5.2%5
10
Pco2 Increased5.2%5
11
Serotonin Syndrome5.2%5
12
Pulmonary Oedema5.2%5
13
Occupational Exposure To Product5.2%5
14
Toxic Epidermal Necrolysis5.2%5
15
Constipation5.2%5

These are voluntary reports and do not establish that enflurane caused these reactions.

Report severity

67.0%Serious65 reports
22.7%Hospitalizations22 reports
11.3%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Enflurane drug interactions

Other drugs that appear in adverse event reports alongside enflurane. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Vecuronium-bromide19.6%19
2
Etomidate18.6%18
3
Succinylcholine-chloride18.6%18
4
Fentanyl15.5%15
5
Nitrous-oxide11.3%11
6
Diazepam11.3%11
7
Propofol10.3%10
8
Isoflurane10.3%10
9
Sevoflurane10.3%10
10
Thiopental-sodium7.2%7
11
Atropine7.2%7
12
Paroxetine7.2%7
13
Halothane7.2%7
14
Droperidol6.2%6
15
Ranitidine6.2%6

Taken alongside

1
Oxygen44.3%43
2
Nitrous-oxide19.6%19
3
Lorazepam17.5%17
4
Fentanyl15.5%15
5
Sufentanil-citrate15.5%15
6
Morphine-sulfate14.4%14
7
Atracurium-besylate10.3%10
8
Thiopental-sodium9.3%9
9
Propofol9.3%9
10
Apomorphine-hydrochloride8.2%8
11
Heparin7.2%7
12
Indomethacin7.2%7
13
Diclofenac7.2%7
14
Dextrose7.2%7
15
Pancuronium-bromide7.2%7

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports enflurane side effects

37.1% of enflurane adverse event reports involve female patients and 29.9% involve male patients. The largest age group is adult at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female37.1%
Male29.9%
Unknown33.0%

Age group

< 21.8%
2–118.8%
12–1710.5%
18–6463.2%
65+15.8%

What is enflurane used for

Conditions and purposes for which patients were taking enflurane when the adverse event was reported.

Accidental ExposureAnaesthesiaAnaesthesia ProcedureAnaesthesiaDental OperationDrug Use For Unknown IndicationEndotracheal IntubationGeneral AnaesthesiaMaintenance Of AnaesthesiaOccupational Exposure To ProductProduct Used For Unknown IndicationProduct Used For Unknown IndicationSedation

Enflurane brand names and reporting trend

Enflurane is sold under the brand name Ethrane.

Brand names

Ethrane92

Quarterly reports (20042024)

20052024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking enflurane with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.