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Elvitegravir Side Effects

The most commonly reported side effects of elvitegravir include bone density decreased, renal injury, and chronic kidney disease, based on 16,371 FDA adverse event reports from 2005 to 2025.

Elvitegravir side effects

Percentages show how often each reaction appears relative to total reports for elvitegravir.

1
Bone Density Decreased43.9%7,187
2
Renal Injury26.2%4,286
3
Chronic Kidney Disease25.3%4,134
4
Skeletal Injury23.4%3,838
5
Tooth Loss22.8%3,733
6
Bone Loss22.1%3,620
7
Osteonecrosis21.8%3,565
8
Renal Failure20.5%3,354
9
Multiple Fractures20.0%3,277
10
Pain17.8%2,920
11
Osteoporosis17.7%2,890
12
Emotional Distress17.4%2,841
13
Anxiety16.1%2,633
14
Anhedonia15.3%2,512
15
Tooth Injury12.1%1,979

These are voluntary reports and do not establish that elvitegravir caused these reactions.

Report severity

80.3%Serious13,138 reports
10.8%Hospitalizations1,768 reports
2.0%Fatal326 reports

Seriousness is determined by the reporter, not by OpenClaim.

Elvitegravir drug interactions

Other drugs that appear in adverse event reports alongside elvitegravir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tenofovir93.7%15,339
2
Emtricitabine93.0%15,221
3
Cobicistat70.4%11,519
4
Efavirenz39.6%6,477
5
Rilpivirine21.7%3,559
6
Dolutegravir1.7%271
7
Ritonavir1.6%266
8
Darunavir1.4%230
9
Lamivudine1.4%230
10
Abacavir1.0%170
11
Bictegravir1.0%164
12
Raltegravir-potassium1.0%161
13
Lopinavir0.6%106
14
Atazanavir-sulfate0.6%96
15
Zidovudine0.6%95

Taken alongside

1
Tenofovir56.6%9,260
2
Emtricitabine56.4%9,238
3
Cobicistat45.1%7,378
4
Bictegravir22.0%3,606
5
Darunavir5.1%828
6
Rilpivirine3.9%641
7
Lamivudine3.8%614
8
Ritonavir3.4%558
9
Dolutegravir3.2%530
10
Ergocalciferol2.8%466
11
Acetaminophen2.8%455
12
Abacavir2.6%426
13
Albuterol2.4%401
14
Lisinopril2.3%375
15
Gabapentin2.2%367

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports elvitegravir side effects

23.3% of elvitegravir adverse event reports involve female patients and 68.7% involve male patients. The largest age group is adult at 94%. These figures reflect who reports side effects, not underlying risk.

Sex

Female23.3%
Male68.7%
Unknown8.0%

Age group

< 20.3%
2–11<0.1%
12–170.2%
18–6493.7%
65+5.7%

What is elvitegravir used for

Conditions and purposes for which patients were taking elvitegravir when the adverse event was reported.

Acquired Immunodeficiency SyndromeAcute Hepatitis CAcute Hiv InfectionAnal CancerAnogenital WartsAntiretroviral TherapyAntiviral TreatmentAsymptomatic Hiv InfectionAcquired Immunodeficiency SyndromeAcute Hiv InfectionAntiretroviral TherapyAntiviral TreatmentAsymptomatic Hiv InfectionBacillary AngiomatosisBursitis

Showing 15 of 88 indications

Elvitegravir brand names and reporting trend

Elvitegravir is sold under brand names including Stribild, Elvitegravir, Cobicistat, Emtricitabine And Tenofovir Alafenamide.

Brand names

Stribild298
Elvitegravir, Cobicistat, Emtricitabine And Tenofovir Alafenamide60

Quarterly reports (20052025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking elvitegravir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.