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Elosulfase Side Effects

The most commonly reported side effects of elosulfase include pyrexia, cough, and vomiting, based on 5,163 FDA adverse event reports from 2014 to 2025.

Elosulfase side effects

Percentages show how often each reaction appears relative to total reports for elosulfase.

1
Pyrexia13.6%703
2
Cough6.3%327
3
Vomiting6.2%321
4
Malaise5.5%285
5
Headache4.8%246
6
Dyspnoea4.3%223
7
Nausea4.2%217
8
Pain4.2%215
9
Nasopharyngitis3.6%187
10
Fatigue3.5%183
11
Pneumonia3.1%159
12
Product Dose Omission3.0%155
13
Oxygen Saturation Decreased2.9%148
14
Arthralgia2.5%130
15
Pain In Extremity2.5%129

These are voluntary reports and do not establish that elosulfase caused these reactions.

Report severity

40.3%Serious2,082 reports
21.0%Hospitalizations1,086 reports
2.4%Fatal123 reports

Seriousness is determined by the reporter, not by OpenClaim.

Elosulfase drug interactions

Other drugs that appear in adverse event reports alongside elosulfase. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Diphenhydramine0.2%9
2
Methylprednisolone0.2%9
3
Lidocaine0.2%9
4
Prilocaine0.2%8
5
Hydrocortisone0.1%7
6
Montelukast-sodium<0.1%4
7
Cetirizine-hydrochloride<0.1%4
8
Omalizumab<0.1%4
9
Desloratadine<0.1%3
10
Dexchlorpheniramine-maleate<0.1%3
11
Vosoritide<0.1%3
12
Ammonium<0.1%2
13
Fentanyl<0.1%2
14
Loratadine<0.1%2
15
Naproxen<0.1%2

Taken alongside

1
Diphenhydramine14.3%739
2
Acetaminophen12.2%628
3
Epinephrine10.6%549
4
Heparin7.1%365
5
Cetirizine-hydrochloride5.5%285
6
Loratadine4.5%232
7
Ibuprofen4.5%230
8
Lidocaine4.3%222
9
Albuterol4.0%204
10
Methylprednisolone3.8%196
11
Ammonium3.2%167
12
Montelukast-sodium3.0%153
13
Prilocaine2.8%142
14
Sodium-chloride2.5%131
15
Fluticasone2.4%123

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports elosulfase side effects

38.2% of elosulfase adverse event reports involve female patients and 29.2% involve male patients. The largest age group is child at 39%. These figures reflect who reports side effects, not underlying risk.

Sex

Female38.2%
Male29.2%
Unknown32.6%

Age group

< 21.4%
2–1138.6%
12–1722.4%
18–6436.9%
65+0.7%

What is elosulfase used for

Conditions and purposes for which patients were taking elosulfase when the adverse event was reported.

Allergy TestComplement Deficiency DiseaseDeafness NeurosensoryDwarfismFabry^s DiseaseGaucher^s DiseaseGlycogen Storage Disease Type IvMucopolysaccharidosisMucopolysaccharidosis IMucopolysaccharidosis IiMucopolysaccharidosis IvMucopolysaccharidosis ViMalignant Palate NeoplasmMucopolysaccharidosisMucopolysaccharidosis Ii

Showing 15 of 23 indications

Elosulfase brand names and reporting trend

Elosulfase is sold under the brand name Vimizim.

Brand names

Vimizim10

Quarterly reports (20142025)

20142016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking elosulfase with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.