OpenClaim

Eletriptan Side Effects

The most commonly reported side effects of eletriptan include migraine, headache, and nausea, based on 8,104 FDA adverse event reports from 2004 to 2025. 11.5% of reports found the drug to be ineffective.

Eletriptan side effects

Percentages show how often each reaction appears relative to total reports for eletriptan.

1
Drug Ineffective11.5%929
2
Migraine9.7%786
3
Headache8.0%646
4
Nausea5.4%440
5
Pain4.9%396
6
Fatigue4.3%347
7
Off Label Use3.7%298
8
Vomiting3.5%286
9
Malaise3.3%268
10
Dizziness3.0%241
11
Condition Aggravated2.5%204
12
Migraine2.4%198
13
Headache2.4%193
14
Insomnia2.3%188
15
Anxiety2.3%185

These are voluntary reports and do not establish that eletriptan caused these reactions.

Report severity

54.5%Serious4,414 reports
18.6%Hospitalizations1,507 reports
1.8%Fatal142 reports

Seriousness is determined by the reporter, not by OpenClaim.

Eletriptan drug interactions

Other drugs that appear in adverse event reports alongside eletriptan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate6.5%526
2
Sumatriptan4.3%350
3
Topiramate4.2%337
4
Erenumab-aooe3.4%273
5
Pregabalin2.9%236
6
Adalimumab2.5%203
7
Ethinyl-estradiol2.2%177
8
Acetaminophen2.2%175
9
Onabotulinumtoxina2.1%174
10
Galcanezumab-gnlm2.1%168
11
Drospirenone1.9%158
12
Ibuprofen1.8%146
13
Gabapentin1.7%141
14
Amitriptyline-hydrochloride1.7%138
15
Rizatriptan-benzoate1.6%131

Taken alongside

1
Acetaminophen16.2%1,311
2
Topiramate11.6%937
3
Ergocalciferol10.8%875
4
Levothyroxine-sodium10.1%820
5
Gabapentin8.2%665
6
Ibuprofen7.9%642
7
Albuterol7.9%641
8
Omeprazole6.8%549
9
Ondansetron6.6%534
10
Fluticasone6.4%518
11
Hydrocodone6.2%505
12
Aspirin6.0%484
13
Duloxetine-hydrochloride6.0%483
14
Alprazolam5.6%451
15
Clonazepam5.4%440

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports eletriptan side effects

80.3% of eletriptan adverse event reports involve female patients and 11.5% involve male patients. The largest age group is adult at 87%. These figures reflect who reports side effects, not underlying risk.

Sex

Female80.3%
Male11.5%
Unknown8.3%

Age group

< 20.8%
2–110.3%
12–171.1%
18–6487.5%
65+10.2%

What is eletriptan used for

Conditions and purposes for which patients were taking eletriptan when the adverse event was reported.

AuraAutoimmune DisorderAbdominal MigraineAbortion InducedAccidental Exposure To Product By ChildAnalgesic TherapyArnold-chiari MalformationArthralgiaBack PainBenign Intracranial HypertensionBone PainBrain OperationBack PainBrain NeoplasmBreakthrough Pain

Showing 15 of 95 indications

Eletriptan brand names and reporting trend

Eletriptan is sold under the brand name Relpax.

Brand names

Relpax1,591

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking eletriptan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.