OpenClaim

Elapegademase Side Effects

The most commonly reported side effects of elapegademase include nasopharyngitis, cough, and covid-19, based on 294 FDA adverse event reports from 2014 to 2025.

Elapegademase side effects

Percentages show how often each reaction appears relative to total reports for elapegademase.

1
Nasopharyngitis12.6%37
2
Cough7.5%22
3
Covid-197.5%22
4
Sinusitis4.4%13
5
Bone Marrow Transplant4.4%13
6
Weight Decreased4.1%12
7
Pneumonia3.4%10
8
Injection Site Pain3.4%10
9
Pyrexia3.4%10
10
Rhinorrhoea3.4%10
11
Off Label Use3.4%10
12
Rash2.7%8
13
Product Dose Omission2.7%8
14
Weight Increased2.7%8
15
Diarrhoea2.7%8

These are voluntary reports and do not establish that elapegademase caused these reactions.

Report severity

25.5%Serious75 reports
15.0%Hospitalizations44 reports
1.4%Fatal4 reports

Seriousness is determined by the reporter, not by OpenClaim.

Elapegademase drug interactions

Other drugs that appear in adverse event reports alongside elapegademase. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ambrisentan0.3%1
2
Ipratropium-bromide0.3%1
3
Palivizumab0.3%1
4
Fluconazole0.3%1
5
Voriconazole0.3%1

Taken alongside

1
Trimethoprim18.7%55
2
Sulfamethoxazole16.3%48
3
Acyclovir9.2%27
4
Fluconazole6.1%18
5
Ergocalciferol5.1%15
6
Calcium4.8%14
7
Levothyroxine-sodium4.4%13
8
Albuterol4.4%13
9
Buspirone-hydrochloride4.1%12
10
Budesonide4.1%12
11
Montelukast-sodium3.7%11
12
Escitalopram-oxalate3.7%11
13
Clonazepam3.4%10
14
Diphenhydramine3.4%10
15
Fluoxetine-hydrochloride3.4%10

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports elapegademase side effects

44.9% of elapegademase adverse event reports involve female patients and 42.2% involve male patients. The largest age group is adult at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.9%
Male42.2%
Unknown12.9%

Age group

< 217.7%
2–1119.9%
12–176.1%
18–6456.4%
65+0.0%

What is elapegademase used for

Conditions and purposes for which patients were taking elapegademase when the adverse event was reported.

Adenosine DeaminaseCombined ImmunodeficiencyCombined ImmunodeficiencyDetoxificationFailure To ThriveImmune System DisorderImmunodeficiencyImmunodeficiencyOff Label UsePneumoniaProduct Used For Unknown IndicationProduct Used For Unknown Indication

Elapegademase brand names and reporting trend

Elapegademase is sold under the brand name Revcovi.

Brand names

Revcovi33

Quarterly reports (20142025)

2014202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking elapegademase with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.