OpenClaim

Efinaconazole Side Effects

The most commonly reported side effects of efinaconazole include fatigue, pain, and headache, based on 1,875 FDA adverse event reports from 2014 to 2025. 20.9% of reports found the drug to be ineffective.

Efinaconazole side effects

Percentages show how often each reaction appears relative to total reports for efinaconazole.

1
Drug Ineffective20.9%391
2
Fatigue11.8%222
3
Pain11.4%214
4
Headache10.2%192
5
Asthenia10.2%192
6
Oedema Peripheral8.5%160
7
Drug Hypersensitivity8.5%160
8
Cough8.3%155
9
Pyrexia8.2%153
10
Dyspnoea8.1%151
11
Anaemia8.0%150
12
Product Dose Omission Issue7.7%144
13
Pneumonia7.6%143
14
Tremor7.6%142
15
Asthma7.5%141

These are voluntary reports and do not establish that efinaconazole caused these reactions.

Report severity

36.3%Serious681 reports
19.7%Hospitalizations370 reports
4.4%Fatal83 reports

Seriousness is determined by the reporter, not by OpenClaim.

Efinaconazole drug interactions

Other drugs that appear in adverse event reports alongside efinaconazole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Nitroglycerin7.6%142
2
Albuterol7.5%141
3
Ipratropium-bromide7.5%141
4
Budesonide7.4%138
5
Acetaminophen7.3%137
6
Dexlansoprazole6.8%128
7
Candesartan-cilexetil6.7%125
8
Lansoprazole6.0%112
9
Montelukast-sodium5.9%110
10
Levothyroxine-sodium5.8%109
11
Pantoprazole-sodium5.7%106
12
Mometasone-furoate5.6%105
13
Quetiapine-fumarate5.6%105
14
Mepolizumab5.6%105
15
Eszopiclone5.6%105

Taken alongside

1
Ergocalciferol12.8%240
2
Acetaminophen10.1%189
3
Levothyroxine-sodium9.0%168
4
Aspirin7.6%143
5
Calcium7.3%137
6
Fluticasone6.1%115
7
Atorvastatin-calcium5.5%104
8
Amlodipine5.3%100
9
Prednisone5.1%96
10
Albuterol5.1%95
11
Ascorbic-acid5.1%95
12
Rosuvastatin4.6%87
13
Pantoprazole-sodium4.6%86
14
Cyanocobalamin4.5%85
15
Omeprazole4.5%85

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports efinaconazole side effects

57.2% of efinaconazole adverse event reports involve female patients and 37.3% involve male patients. The largest age group is elderly at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.2%
Male37.3%
Unknown5.5%

Age group

< 20.2%
2–110.4%
12–170.9%
18–6443.4%
65+55.1%

What is efinaconazole used for

Conditions and purposes for which patients were taking efinaconazole when the adverse event was reported.

Antifungal TreatmentAdverse EventAntifungal TreatmentBody TineaCandida InfectionDermatitis ContactDermatophytosis Of NailDiabetes MellitusDermatophytosis Of NailEczemaFungal InfectionFungal Skin InfectionFoetal Exposure During PregnancyFungal Foot InfectionFungal Infection

Showing 15 of 47 indications

Efinaconazole brand names and reporting trend

Efinaconazole is sold under the brand name Efinaconazole.

Brand names

Efinaconazole254

Quarterly reports (20142025)

20142016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking efinaconazole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.