OpenClaim

Efbemalenograstim Side Effects

The most commonly reported side effects of efbemalenograstim include febrile neutropenia, neutropenia, and pyrexia, based on 1,740 FDA adverse event reports from 2004 to 2025.

Efbemalenograstim side effects

Percentages show how often each reaction appears relative to total reports for efbemalenograstim.

1
Febrile Neutropenia10.3%180
2
Neutropenia9.0%157
3
Pyrexia8.9%155
4
Off Label Use5.9%103
5
Pneumonia5.7%99
6
Nausea4.8%83
7
Fatigue4.8%83
8
Sepsis4.8%83
9
Thrombocytopenia4.7%81
10
Anaemia4.6%80
11
Dyspnoea4.5%79
12
Diarrhoea4.3%75
13
Vomiting4.0%69
14
Asthenia3.4%59
15
Febrile Neutropenia3.2%55

These are voluntary reports and do not establish that efbemalenograstim caused these reactions.

Report severity

99.0%Serious1,723 reports
57.0%Hospitalizations992 reports
26.3%Fatal458 reports

Seriousness is determined by the reporter, not by OpenClaim.

Efbemalenograstim drug interactions

Other drugs that appear in adverse event reports alongside efbemalenograstim. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cyclophosphamide19.9%346
2
Doxorubicin-hydrochloride14.4%250
3
Rituximab13.0%226
4
Vincristine-sulfate12.7%221
5
Etoposide10.4%181
6
Cytarabine9.9%173
7
Dexamethasone9.3%162
8
Prednisolone8.6%149
9
Prednisone8.3%145
10
Carboplatin8.2%143
11
Filgrastim8.2%142
12
Methotrexate7.9%137
13
Fludarabine-phosphate7.5%130
14
Pegfilgrastim6.1%106
15
Busulfan6.0%105

Taken alongside

1
Acetaminophen17.2%299
2
Acyclovir16.6%288
3
Sulfamethoxazole14.2%247
4
Methylprednisolone12.1%210
5
Trimethoprim12.0%209
6
Dexamethasone11.9%207
7
Furosemide11.8%205
8
Fluconazole9.5%165
9
Meropenem9.3%162
10
Prednisolone9.3%161
11
Levofloxacin9.1%158
12
Omeprazole9.0%156
13
Cyclophosphamide8.5%148
14
Allopurinol8.5%148
15
Ondansetron8.5%148

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports efbemalenograstim side effects

41.1% of efbemalenograstim adverse event reports involve female patients and 48.6% involve male patients. The largest age group is adult at 48%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.1%
Male48.6%
Unknown10.2%

Age group

< 23.0%
2–117.2%
12–174.4%
18–6448.1%
65+37.3%

What is efbemalenograstim used for

Conditions and purposes for which patients were taking efbemalenograstim when the adverse event was reported.

Acute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RecurrentAdverse EventAgranulocytosisAnaemiaAplasiaAplastic AnaemiaAsthmaAutoimmune NeutropeniaAutologous Haematopoietic Stem Cell TransplantAcute LeukaemiaAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAdverse Event

Showing 15 of 133 indications

Efbemalenograstim brand names and reporting trend

Efbemalenograstim is sold under the brand name Ryzneuta.

Brand names

Ryzneuta2,496

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking efbemalenograstim with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.