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Edrophonium Side Effects

The most commonly reported side effects of edrophonium include drug effect decreased, bronchospasm, and crepitations, based on 38 FDA adverse event reports from 2004 to 2021. 5.3% of reports found the drug to be ineffective.

Edrophonium side effects

Percentages show how often each reaction appears relative to total reports for edrophonium.

1
Drug Effect Decreased7.9%3
2
Bronchospasm5.3%2
3
Crepitations5.3%2
4
Pulmonary Oedema5.3%2
5
Bradycardia5.3%2
6
Cardiac Arrest5.3%2
7
Cardiac Arrest5.3%2
8
Drug Ineffective5.3%2
9
Salivary Hypersecretion5.3%2
10
Bradycardia5.3%2
11
Miosis5.3%2
12
Ophthalmoplegia5.3%2
13
Agitation5.3%2
14
Accidental Overdose5.3%2
15
Cholinergic Syndrome5.3%2

These are voluntary reports and do not establish that edrophonium caused these reactions.

Report severity

73.7%Serious28 reports
26.3%Hospitalizations10 reports
13.2%Fatal5 reports

Seriousness is determined by the reporter, not by OpenClaim.

Edrophonium drug interactions

Other drugs that appear in adverse event reports alongside edrophonium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Atropine18.4%7
2
Adalimumab7.9%3
3
Sevoflurane5.3%2
4
Dexmedetomidine-hydrochloride2.6%1
5
Pazopanib-hydrochloride2.6%1
6
Fingolimod2.6%1
7
Drospirenone2.6%1
8
Ethinyl-estradiol2.6%1
9
Rocuronium-bromide2.6%1
10
Propofol2.6%1
11
Isoflurane2.6%1
12
Midazolam2.6%1
13
Fentanyl2.6%1
14
Nitrous-oxide2.6%1
15
Abatacept2.6%1

Taken alongside

1
Atropine13.2%5
2
Ondansetron13.2%5
3
Ergocalciferol13.2%5
4
Metoprolol13.2%5
5
Propofol10.5%4
6
Aspirin10.5%4
7
Midazolam10.5%4
8
Atorvastatin-calcium7.9%3
9
Atenolol7.9%3
10
Hydrocodone7.9%3
11
Fentanyl7.9%3
12
Simvastatin7.9%3
13
Ranitidine7.9%3
14
Atracurium-besylate5.3%2
15
Cefazolin-sodium5.3%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports edrophonium side effects

31.6% of edrophonium adverse event reports involve female patients and 44.7% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female31.6%
Male44.7%
Unknown23.7%

Age group

< 23.7%
2–110.0%
12–173.7%
18–6459.3%
65+33.3%

What is edrophonium used for

Conditions and purposes for which patients were taking edrophonium when the adverse event was reported.

Anaesthesia ReversalBladder DisorderDrug Use For Unknown IndicationEye Movement DisorderGlaucomaMyasthenia GravisNeuromuscular Blockade ReversalProduct Used For Unknown IndicationProstatic DisorderProduct Used For Unknown IndicationTensilon TestUrinary Tract Disorder

Edrophonium brand names and reporting trend

Edrophonium is sold under the brand name Tensilon Preservative Free.

Brand names

Tensilon Preservative Free11

Quarterly reports (20042021)

200420202021

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking edrophonium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.