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Econazole Side Effects

The most commonly reported side effects of econazole include acute kidney injury, fatigue, and rash, based on 2,290 FDA adverse event reports from 2004 to 2025. 4.8% of reports found the drug to be ineffective.

Econazole side effects

Percentages show how often each reaction appears relative to total reports for econazole.

1
Drug Ineffective4.8%110
2
Acute Kidney Injury4.3%99
3
Fatigue4.1%94
4
Rash4.1%93
5
Nausea3.8%88
6
Fall3.6%83
7
Chronic Kidney Disease3.6%82
8
Pruritus3.5%80
9
Off Label Use3.5%80
10
Diarrhoea3.4%78
11
Renal Failure3.4%77
12
Pain3.1%72
13
Dyspnoea2.8%64
14
Anaemia2.7%61
15
Arthralgia2.7%61

These are voluntary reports and do not establish that econazole caused these reactions.

Report severity

75.7%Serious1,734 reports
45.9%Hospitalizations1,051 reports
7.2%Fatal166 reports

Seriousness is determined by the reporter, not by OpenClaim.

Econazole drug interactions

Other drugs that appear in adverse event reports alongside econazole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Furosemide5.4%124
2
Acetaminophen5.4%123
3
Amoxicillin4.9%113
4
Enoxaparin-sodium4.6%106
5
Pantoprazole-sodium4.1%94
6
Omeprazole3.2%73
7
Esomeprazole3.1%72
8
Lenalidomide3.0%69
9
Fluconazole2.7%61
10
Lansoprazole2.6%60
11
Clavulanate-potassium2.6%59
12
Allopurinol2.6%59
13
Tramadol-hydrochloride2.5%57
14
Ciprofloxacin2.4%54
15
Warfarin2.2%51

Taken alongside

1
Acetaminophen24.0%549
2
Furosemide15.0%344
3
Aspirin14.1%324
4
Levothyroxine-sodium13.6%312
5
Albuterol13.1%301
6
Ergocalciferol13.0%297
7
Omeprazole12.1%276
8
Atorvastatin-calcium12.0%274
9
Amlodipine11.0%253
10
Fluticasone10.8%247
11
Oxycodone10.7%244
12
Pantoprazole-sodium10.1%231
13
Insulin10.0%230
14
Metformin9.8%224
15
Prednisone9.6%219

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports econazole side effects

52.9% of econazole adverse event reports involve female patients and 39.7% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.9%
Male39.7%
Unknown7.3%

Age group

< 20.9%
2–111.1%
12–170.9%
18–6437.2%
65+59.9%

What is econazole used for

Conditions and purposes for which patients were taking econazole when the adverse event was reported.

Accidental Exposure To ProductActinomycotic Skin InfectionAdverse EventAnal PruritusAngular CheilitisAntifungal ProphylaxisAntifungal TreatmentAphthous UlcerArteriovenous FistulaAspergillosisAllergy ProphylaxisAntifungal ProphylaxisAntifungal TreatmentAphthous UlcerBody Tinea

Showing 15 of 135 indications

Econazole brand names and reporting trend

Econazole is sold under the brand name Spectazole.

Brand names

Spectazole2,292

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking econazole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.