Percentages show how often each reaction appears relative to total reports for duloxetine.
3 Drug Ineffective 6.6% 12,538
12 Drug Withdrawal Syndrome 3.8% 7,208
These are voluntary reports and do not establish that duloxetine caused these reactions.
Report severity
61.4% Serious 116,121 reports
26.2% Hospitalizations 49,616 reports
6.1% Fatal 11,552 reports
Seriousness is determined by the reporter, not by OpenClaim.
Duloxetine drug interactions
Other drugs that appear in adverse event reports alongside duloxetine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
5 Quetiapine-fumarate 2.5% 4,715
14 Tramadol-hydrochloride 1.3% 2,377
Taken alongside
3 Ergocalciferol 12.3% 23,294
4 Levothyroxine-sodium 11.9% 22,434
7 Atorvastatin-calcium 8.5% 16,160
12 Pantoprazole-sodium 6.8% 12,865
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
Who reports duloxetine side effects
69.5% of duloxetine adverse event reports involve female patients and 24.2% involve male patients. The largest age group is adult at 69%. These figures reflect who reports side effects, not underlying risk.
Sex
Female 69.5%
Male 24.2%
Unknown 6.3%
Age group
< 2 0.5%
2–11 0.1%
12–17 0.7%
18–64 69.1%
65+ 29.5%
What is duloxetine used for
Conditions and purposes for which patients were taking duloxetine when the adverse event was reported.
Abdominal Discomfort Abdominal Pain Abdominal Pain Lower Abdominal Pain Upper Abnormal Behaviour Abnormal Dreams Abulia Accident Accidental Exposure Accidental Exposure To Product Accidental Exposure To Product By Child Acne Activities Of Daily Living Impaired Acute Cutaneous Lupus Erythematosus Acute Hepatic Failure
Showing 15 of 1,404 indications
ABDOMINAL DISCOMFORT ABDOMINAL PAIN ABDOMINAL PAIN LOWER ABDOMINAL PAIN UPPER ABNORMAL BEHAVIOUR ABNORMAL DREAMS ABULIA ACCIDENT ACCIDENTAL EXPOSURE ACCIDENTAL EXPOSURE TO PRODUCT ACCIDENTAL EXPOSURE TO PRODUCT BY CHILD ACNE ACTIVITIES OF DAILY LIVING IMPAIRED ACUTE CUTANEOUS LUPUS ERYTHEMATOSUS ACUTE HEPATIC FAILURE ACUTE KIDNEY INJURY ACUTE STRESS DISORDER ADENOCARCINOMA PANCREAS ADJUSTMENT DISORDER ADJUSTMENT DISORDER WITH ANXIETY ADJUSTMENT DISORDER WITH DEPRESSED MOOD ADJUSTMENT DISORDER WITH MIXED ANXIETY AND DEPRESSED MOOD ADJUSTMENT DISORDER WITH MIXED DISTURBANCE OF EMOTION AND CONDUCT ADJUVANT THERAPY ADVERSE DRUG REACTION ADVERSE EVENT AFFECT LABILITY AFFECTIVE DISORDER AGGRESSION AGITATED DEPRESSION AGITATION AGORAPHOBIA ALCOHOL ABUSE ALCOHOL DEPENDENCE SYNDROME ALCOHOL USE DISORDER ALCOHOL WITHDRAWAL SYNDROME ALCOHOLISM ALLODYNIA AMNESIA AMPUTATION STUMP PAIN AMYOTROPHIC LATERAL SCLEROSIS ANAEMIA ANAESTHESIA ANALGESIA ANALGESIC THERAPY ANAPHYLACTIC REACTION ANEURYSM ANGER ANGINA PECTORIS ANGINA UNSTABLE ANGIOPATHY ANGIOSARCOMA ANHEDONIA ANKYLOSING SPONDYLITIS ANOREXIA ANOREXIA NERVOSA ANTACID THERAPY ANTI-MYELIN-ASSOCIATED GLYCOPROTEIN ASSOCIATED POLYNEUROPATHY ANTIBIOTIC THERAPY ANTICIPATORY ANXIETY ANTICOAGULANT THERAPY ANTIDEPRESSANT DRUG CLEARANCE ANTIDEPRESSANT DRUG LEVEL ANTIDEPRESSANT THERAPY ANTIINFLAMMATORY THERAPY ANTIPLATELET THERAPY ANTIVIRAL PROPHYLAXIS ANXIETY ANXIETY DISORDER ANXIOLYTIC THERAPY ANXIOUS DEPRESSION APATHY APPETITE DISORDER APRAXIA ARACHNOIDITIS ARNOLD-CHIARI MALFORMATION ARRHYTHMIA ARTERIOSCLEROSIS CORONARY ARTERY ARTHRALGIA ARTHRITIS ARTHRITIS ENTEROPATHIC ARTHROPATHY ASPERGER'S DISORDER ASPERGER^S DISORDER ASTHENIA ASTHMA ATRIAL FIBRILLATION ATTENTION DEFICIT HYPERACTIVITY DISORDER ATTENTION DEFICIT/HYPERACTIVITY DISORDER AUTISM AUTISM SPECTRUM DISORDER AUTOIMMUNE DISORDER AUTOIMMUNE HEPATITIS AUTOIMMUNE NEUROPATHY AUTOIMMUNE THYROIDITIS AUTONOMIC NERVOUS SYSTEM IMBALANCE AUTONOMIC NEUROPATHY AXONAL NEUROPATHY Abdominal distension Abdominal pain Abdominal pain lower Abnormal behaviour Accidental exposure to product by child Acute abdomen Acute lymphocytic leukaemia Adenocarcinoma gastric Adjustment disorder Adjustment disorder with anxiety Adjustment disorder with depressed mood Adrenal disorder Adverse drug reaction Adverse event Affect lability Affective disorder Agitated depression Agitation Alcohol use disorder Allodynia Amyotrophic lateral sclerosis Anaesthesia Analgesic intervention supportive therapy Analgesic therapy Anger Anhedonia Ankylosing spondylitis Anorexia nervosa Anticoagulant therapy Antidepressant therapy Antifungal prophylaxis Antiinflammatory therapy Antipsychotic therapy Anxiety Anxiety disorder Anxiolytic therapy Apathy Apnoea Arnold-Chiari malformation Arthralgia Arthritis Arthritis bacterial Arthropathy Asthenia Asthma Atrial fibrillation Attention deficit hyperactivity disorder Autism spectrum disorder Autoimmune disorder Autoimmune hepatitis Autoimmune thyroiditis Axial spondyloarthritis Axillary pain BACK DISORDER BACK INJURY BACK PAIN BALANCE DISORDER BARRETT'S OESOPHAGUS BEDRIDDEN BEHAVIOURAL THERAPY BEHCET^S SYNDROME BENIGN PROSTATIC HYPERPLASIA BIPOLAR DEPRESSION BIPOLAR DISORDER BIPOLAR I DISORDER BIPOLAR II DISORDER BLADDER CANCER BLADDER DISORDER BLADDER IRRITATION BLADDER PAIN BLADDER SPASM BLOOD CHOLESTEROL BLOOD CHOLESTEROL INCREASED BLOOD COUNT ABNORMAL BLOOD PHOSPHORUS DECREASED BLOOD PRESSURE BLOOD PRESSURE ABNORMAL BLOOD PRESSURE HIGH BLOOD PRESSURE INADEQUATELY CONTROLLED BLOOD PRESSURE INCREASED BLOOD PRESSURE MEASUREMENT BLOOD SELENIUM DECREASED BLOOD TRIGLYCERIDES BLOOD TRIGLYCERIDES INCREASED BLUNTED AFFECT BONE DISORDER BONE MARROW FAILURE BONE PAIN BORDERLINE PERSONALITY DISORDER BRACHIAL PLEXOPATHY BRACHIAL PLEXUS INJURY BRACHIORADIAL PRURITUS BRAIN INJURY BREAKTHROUGH PAIN BREAST CANCER BREAST CANCER FEMALE BREAST PAIN BRONCHITIS CHRONIC BULIMIA NERVOSA BURNING FEET SYNDROME BURNING MOUTH SYNDROME BURNING SENSATION BURNING TONGUE BURNOUT SYNDROME BURSITIS Back disorder Back injury Back pain Behaviour disorder Behcet^s syndrome Biliary dyskinesia Bipolar I disorder Bipolar II disorder Bipolar disorder Bladder cancer Bladder disorder Bladder dysfunction Bladder irritation Blood cholesterol abnormal Blood cholesterol increased Blood glucose abnormal Blood pressure abnormal Blood pressure measurement Blood uric acid increased Blue toe syndrome Bone pain Borderline personality disorder Bradyphrenia Breakthrough pain Breast cancer Breast cancer female Breast cancer metastatic Breast ulceration Bulbospinal muscular atrophy congenital Bulimia nervosa Burning mouth syndrome Burning sensation Burnout syndrome CANCER PAIN CARDIAC DISORDER CARDIAC MURMUR CARPAL TUNNEL DECOMPRESSION CARPAL TUNNEL SYNDROME CARTILAGE ATROPHY CATAPLEXY CAUDA EQUINA SYNDROME CELLULITIS CENTRAL PAIN SYNDROME CEREBELLAR ATAXIA CEREBRAL DISORDER CEREBRAL HAEMORRHAGE CEREBROVASCULAR ACCIDENT CERVICAL RADICULOPATHY CERVICAL ROOT PAIN CERVICAL SPINAL STENOSIS CERVICALGIA CERVICOBRACHIAL SYNDROME CERVICOGENIC HEADACHE CHEMOTHERAPY CHEST DISCOMFORT CHEST PAIN CHIKUNGUNYA VIRUS INFECTION CHOKING SENSATION CHRONIC BACK PAIN CHRONIC DEPRESSION CHRONIC DISEASE CHRONIC FATIGUE SYNDROME CHRONIC GRAFT VERSUS HOST DISEASE CHRONIC IDIOPATHIC PAIN SYNDROME CHRONIC INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY CHRONIC LYMPHOCYTIC LEUKAEMIA CHRONIC OBSTRUCTIVE PULMONARY DISEASE CHRONIC PAIN CHRONIC SPONTANEOUS URTICARIA CLOSTRIDIUM DIFFICILE INFECTION CLUSTER HEADACHE COAGULOPATHY COCCYDYNIA COELIAC DISEASE COGNITIVE DISORDER COLECTOMY COLITIS COLITIS MICROSCOPIC COLITIS ULCERATIVE COLON CANCER COMPLETED SUICIDE COMPLEX REGIONAL PAIN SYNDROME COMPRESSION FRACTURE COMPUTER VISION SYNDROME CONFUSIONAL STATE CONNECTIVE TISSUE DISORDER CONSTIPATION CONSTIPATION PROPHYLAXIS CONVERSION DISORDER CONVULSION CONVULSION PROPHYLAXIS COORDINATION ABNORMAL CORONARY ARTERIAL STENT INSERTION COSTOCHONDRITIS COTARD^S SYNDROME COUGH COVID-19 CRANIAL NERVE DISORDER CRANIAL NERVE INJURY CRANIOCEREBRAL INJURY CREST SYNDROME CROHN'S DISEASE CROHN^S DISEASE CRYING CUTANEOUS LUPUS ERYTHEMATOSUS CYCLIC VOMITING SYNDROME CYST CYSTITIS CYSTITIS INTERSTITIAL CYSTITIS ULCERATIVE CYTOKINE RELEASE SYNDROME Cancer pain Cardiovascular disorder Carpal tunnel decompression Carpal tunnel syndrome Cataplexy Catatonia Cauda equina syndrome Central pain syndrome Cerebral disorder Cerebrovascular accident Cervical radiculopathy Cervical spinal stenosis Chest pain Choking sensation Chorea Chronic fatigue syndrome Chronic inflammatory demyelinating polyradiculoneuropathy Chronic spontaneous urticaria Cluster headache Coeliac disease Cognitive disorder Colitis microscopic Colorectal cancer Completed suicide Complex regional pain syndrome Compression fracture Congenital lymphoedema Conjunctival hyperaemia Constipation Conversion disorder Costochondritis Craniocerebral injury Crohn^s disease Cyclothymic disorder Cystitis Cystitis interstitial DEATH DEATH OF PARENT DEATH OF RELATIVE DECREASED APPETITE DECREASED INTEREST DECUBITUS ULCER DEEP VEIN THROMBOSIS DELAYED SLEEP PHASE DELIRIUM DELUSIONAL DISORDER, SOMATIC TYPE DELUSIONAL DISORDER, UNSPECIFIED TYPE DEMENTIA DEMENTIA ALZHEIMER'S TYPE DEMENTIA ALZHEIMER^S TYPE DEMYELINATING POLYNEUROPATHY DEPRESSED LEVEL OF CONSCIOUSNESS DEPRESSED MOOD DEPRESSION DEPRESSION POSTOPERATIVE DEPRESSION SUICIDAL DEPRESSIVE DELUSION DEPRESSIVE SYMPTOM DERMATOMYOSITIS DETOXIFICATION DIABETES MELLITUS DIABETES MELLITUS NON-INSULIN-DEPENDENT DIABETIC AMYOTROPHY DIABETIC AUTONOMIC NEUROPATHY DIABETIC COMPLICATION DIABETIC FOOT DIABETIC GANGRENE DIABETIC NEPHROPATHY DIABETIC NEUROPATHY DIABETIC RETINOPATHY DIARRHOEA DIFFUSE LARGE B-CELL LYMPHOMA DISABILITY DISCOMFORT DISEASE RECURRENCE DISSOCIATIVE DISORDER DISSOCIATIVE IDENTITY DISORDER DISTURBANCE IN ATTENTION DISTURBANCE IN SEXUAL AROUSAL DIZZINESS DRUG ABUSE DRUG ABUSER DRUG ADMINISTRATION ERROR DRUG DEPENDENCE DRUG DISPENSING ERROR DRUG EXPOSURE DURING PREGNANCY DRUG INEFFECTIVE DRUG RESISTANCE DRUG THERAPY DRUG THERAPY CHANGED DRUG USE FOR UNKNOWN INDICATION DRUG WITHDRAWAL SYNDROME DYSAESTHESIA DYSGEUSIA DYSKINESIA DYSPEPSIA DYSPHAGIA DYSPHORIA DYSPNOEA DYSTHYMIC DISORDER DYSTONIA DYSURIA Decreased appetite Decreased immune responsiveness Deformity Delusion Delusion of parasitosis Dementia Dementia Alzheimer^s type Dementia with Lewy bodies Demyelinating polyneuropathy Depressed level of consciousness Depressed mood Depression Depressive symptom Dermatitis atopic Dermatomyositis Diabetes mellitus Diabetic complication Diabetic foot Diabetic nephropathy Diabetic neuropathy Diabetic retinopathy Discouragement Dizziness Drooping shoulder syndrome Drug abuse Drug dependence Drug intolerance Drug therapy Drug withdrawal maintenance therapy Drug withdrawal syndrome Dysaesthesia Dyskinesia Dyslipidaemia Dysmenorrhoea Dyspepsia Dysphagia Dystonia EAR DISORDER EAR PAIN EATING DISORDER ECONOMIC PROBLEM EHLERS-DANLOS SYNDROME ELECTROLYTE IMBALANCE ELEVATED MOOD EMOTIONAL DISORDER ENDOMETRIOSIS ENERGY INCREASED EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS EPIDURAL ANAESTHESIA EPILEPSY ERYSIPELAS ERYTHROMELALGIA EUPHORIC MOOD EVIDENCE BASED TREATMENT EX-TOBACCO USER EXOSTOSIS EXPOSURE DURING PREGNANCY EXTRAPYRAMIDAL DISORDER EYE BURNS EYE PAIN Ear pain Eating disorder Electrocardiogram QT prolonged Embolic cerebral infarction Emotional disorder Encephalopathy Endometriosis Eosinophilic granulomatosis with polyangiitis Epilepsy Erythromelalgia Essential tremor Euphoric mood Ewing^s sarcoma Exposure during pregnancy Eye inflammation Eye pain FACE INJURY FACIAL NERVE DISORDER FACIAL NEURALGIA FACIAL PAIN FAILURE TO THRIVE FAMILIAL MEDITERRANEAN FEVER FAMILIAL RISK FACTOR FASCIITIS FATIGUE FEAR FEELING ABNORMAL FEELING GUILTY FEELING OF RELAXATION FIBROMA FIBROMYALGIA FIBROSIS FLASHBACK FLAT AFFECT FLATULENCE FLUID RETENTION FOETAL EXPOSURE DURING PREGNANCY FOOT DEFORMITY FOOT FRACTURE FREEZING PHENOMENON FRUSTRATION FULL BLOOD COUNT ABNORMAL FULL BLOOD COUNT DECREASED FUNCTIONAL GASTROINTESTINAL DISORDER Facial discomfort Facial pain Fatigue Fear Febrile neutropenia Feeling abnormal Feeling cold Feeling of despair Feeling of relaxation Fibromyalgia Flat affect Foetal exposure during pregnancy Foetal exposure timing unspecified Fracture pain Fracture treatment Freezing phenomenon Functional gastrointestinal disorder GAIT DISTURBANCE GALLBLADDER PAIN GASTRIC DISORDER GASTRIC PH DECREASED GASTROINTESTINAL DISORDER GASTROINTESTINAL MOTILITY DISORDER GASTROINTESTINAL PAIN GASTROOESOPHAGEAL REFLUX DISEASE GENERAL PHYSICAL CONDITION GENERAL SYMPTOM GENERALISED ANXIETY DISORDER GENERALISED TONIC-CLONIC SEIZURE GENERALIZED ANXIETY DISORDER GENITAL DISORDER FEMALE GLAUCOMA GLOSSODYNIA GLOSSOPHARYNGEAL NEURALGIA GLUCOSE TOLERANCE IMPAIRED GOUT GRANDIOSITY GROIN PAIN GROWING PAINS GUILLAIN-BARRE SYNDROME Gait disturbance Gastrointestinal disorder Gastrointestinal pain Gastrooesophageal reflux disease Generalised anxiety disorder Glossodynia Glossopharyngeal neuralgia Gout HAEMORRHAGE HAEMORRHOIDS HALLUCINATION HALLUCINATION, AUDITORY HEAD DEFORMITY HEAD INJURY HEADACHE HEART RATE INCREASED HEMIPLEGIA HEREDITARY MOTOR AND SENSORY NEUROPATHY HERNIA HERNIA PAIN HERPES ZOSTER HIATUS HERNIA HICCUPS HIP FRACTURE HISTRIONIC PERSONALITY DISORDER HIV PERIPHERAL NEUROPATHY HOMICIDAL IDEATION HOMOSEXUALITY HORMONE LEVEL ABNORMAL HORMONE REPLACEMENT THERAPY HORMONE THERAPY HOT FLUSH HYPERACUSIS HYPERCHOLESTEROLAEMIA HYPERHIDROSIS HYPERLIPIDAEMIA HYPERSENSITIVITY HYPERSOMNIA HYPERTENSION HYPERTHYROIDISM HYPERTONIC BLADDER HYPOAESTHESIA HYPOAESTHESIA FACIAL HYPOGLYCAEMIA HYPOMAGNESAEMIA HYPOMANIA HYPONATRAEMIA HYPOPITUITARISM HYPOTHYROIDISM HYSTERECTOMY Hallucination, auditory Hallucination, visual Headache Hemicrania continua Hemiplegia Hemiplegic migraine Hepatic function abnormal Hereditary neuropathic amyloidosis Hernia Herpes zoster Herpes zoster disseminated Hidradenitis Hormone therapy Hot flush Hypermobility syndrome Hyperparathyroidism Hypersensitivity Hypertension Hypertonic bladder Hyperventilation Hypoaesthesia Hypoglycaemia Hyponatraemia IDIOPATHIC INTRACRANIAL HYPERTENSION ILL-DEFINED DISORDER IMPAIRED GASTRIC EMPTYING IMPULSE-CONTROL DISORDER IMPULSIVE BEHAVIOUR INAPPROPRIATE AFFECT INCONTINENCE INFECTION INFLAMMATION INFLUENZA INFLUENZA LIKE ILLNESS INITIAL INSOMNIA INJURY INSOMNIA INTELLECTUAL DISABILITY INTENTIONAL OVERDOSE INTENTIONAL PRODUCT MISUSE INTENTIONAL SELF-INJURY INTERCEPTED MEDICATION ERROR INTERCOSTAL NEURALGIA INTERSTITIAL LUNG DISEASE INTERVERTEBRAL DISC DEGENERATION INTERVERTEBRAL DISC DISORDER INTERVERTEBRAL DISC OPERATION INTERVERTEBRAL DISC PROTRUSION INTESTINAL FUNCTIONAL DISORDER IRRITABILITY IRRITABLE BOWEL SYNDROME ISCHAEMIC LIMB PAIN Idiopathic environmental intolerance Ill-defined disorder Illness Immunodeficiency common variable Inappropriate affect Incontinence Infection Inflammation Inflammatory pain Injection site pain Injury Insomnia Intentional overdose Intentional product misuse Intentional self-injury Intervertebral disc compression Intervertebral disc degeneration Intervertebral disc disorder Intervertebral disc protrusion Intracranial mass Intracranial pressure increased Irritability Irritable bowel syndrome JOINT INJURY JOINT PAIN JOINT STIFFNESS JOINT SWELLING JUVENILE MYOCLONIC EPILEPSY Joint stiffness Juvenile idiopathic arthritis KNEE ARTHROPLASTY LARYNGOSPASM LEARNING DISABILITY LEG AMPUTATION LEG PAIN LETHARGY LEUKOCYTOCLASTIC VASCULITIS LIBIDO DECREASED LIGAMENT SPRAIN LIMB DISCOMFORT LIMB INJURY LOW BACK PAIN LUMBAR RADICULOPATHY LUMBAR SPINAL STENOSIS LUMBOSACRAL RADICULOPATHY LUNG ADENOCARCINOMA LUNG DISORDER LUPUS-LIKE SYNDROME LYME DISEASE Lacrimation increased Limb discomfort Lip swelling Lumbar hernia Lumbar radiculopathy Lumbar spinal stenosis Lupus nephritis Lyme disease MAJOR DEPRESSION MAJOR DEPRESSIVE DISORDER NOS MALAISE MANIA MARFAN'S SYNDROME MATERNAL EXPOSURE DURING BREAST FEEDING MATERNAL EXPOSURE TIMING UNSPECIFIED MEDICATION ERROR MEMORY IMPAIRMENT MENINGITIS MENISCUS INJURY MENOPAUSAL DEPRESSION MENOPAUSAL DISORDER MENOPAUSAL SYMPTOMS MENOPAUSE MENTAL DISABILITY MENTAL DISORDER MENTAL FATIGUE MENTAL RETARDATION MENTAL STATUS CHANGES MERALGIA PARAESTHETICA MERYCISM METASTASES TO BONE METASTASES TO SPINE MICTURITION URGENCY MIGRAINE MIGRAINE PROPHYLAXIS MIGRAINE WITH AURA MIXED ANXIETY AND DEPRESSIVE DISORDER MIXED CONNECTIVE TISSUE DISEASE MOBILITY DECREASED MONOCLONAL GAMMOPATHY MONONEUROPATHY MULTIPLEX MONOPLEGIA MOOD ALTERED MOOD DISORDER DUE TO A GENERAL MEDICAL CONDITION MOOD DISORDER NOS MOOD SWINGS MORNING SICKNESS MOTOR NEURONE DISEASE MOVEMENT DISORDER MULTIPLE DRUG THERAPY MULTIPLE SCLEROSIS MULTIPLE SCLEROSIS RELAPSE MUSCLE CONTRACTIONS INVOLUNTARY MUSCLE DISCOMFORT MUSCLE DISORDER MUSCLE INJURY MUSCLE PAIN MUSCLE RELAXANT THERAPY MUSCLE SPASMS MUSCLE SPASTICITY MUSCLE TIGHTNESS MUSCLE TWITCHING MUSCULAR DYSTROPHY MUSCULAR WEAKNESS MUSCULOSKELETAL CHEST PAIN MUSCULOSKELETAL DISCOMFORT MUSCULOSKELETAL DISORDER MUSCULOSKELETAL INJURY MUSCULOSKELETAL PAIN MUSCULOSKELETAL STIFFNESS MYALGIA MYELITIS TRANSVERSE MYELOFIBROSIS MYELOPATHY MYOCARDIAL CALCIFICATION MYOCARDIAL INFARCTION MYOCLONUS MYOFASCIAL PAIN SYNDROME MYOPATHY MYOSITIS MYXOFIBROSARCOMA Macule Major depression Malaise Maternal exposure during pregnancy Maternal exposure timing unspecified Medication error Meniscus injury Menopausal depression Menstruation irregular Mental disorder Metabolic disorder Microscopic polyangiitis Micturition urgency Middle cerebral artery stroke Migraine Migraine prophylaxis Migraine with aura Migraine without aura Mixed anxiety and depressive disorder Mixed dementia Mood altered Mood swings Movement disorder Multiple sclerosis Muscle disorder Muscle relaxant therapy Muscle spasms Muscular weakness Musculoskeletal disorder Musculoskeletal pain Musculoskeletal stiffness Myalgia Myocardial infarction Myoclonus Myofascial pain syndrome Myofascial spasm Myositis NARCOLEPSY NASOPHARYNGITIS NAUSEA NECK INJURY NECK PAIN NECK SURGERY NEGATIVE THOUGHTS NEOPLASM MALIGNANT NEPHROLITHIASIS NEPHROPATHY NERVE COMPRESSION NERVE DEGENERATION NERVE INJURY NERVE PAIN NERVE ROOT COMPRESSION NERVOUS SYSTEM DISORDER NERVOUSNESS NEURALGIA NEURITIS NEURODERMATITIS NEUROFIBROMATOSIS NEUROGENIC BLADDER NEUROLOGICAL SYMPTOM NEUROMUSCULAR BLOCKING THERAPY NEUROMYELITIS OPTICA SPECTRUM DISORDER NEUROMYOPATHY NEUROPATHIC ARTHROPATHY NEUROPATHIC PAIN NEUROPATHY NEUROPATHY PERIPHERAL NEUROSIS NEUROTOXICITY NEW DAILY PERSISTENT HEADACHE NICOTINE DEPENDENCE NIGHT SWEATS NIGHTMARE NON-CARDIAC CHEST PAIN NOTALGIA PARAESTHETICA Narcolepsy Nasal congestion Nausea Neck pain Neck surgery Nerve block Nerve compression Nerve injury Nervous system disorder Nervousness Neuralgia Neuritis Neurodermatitis Neurodevelopmental disorder Neuroma Neuromuscular pain Neuromuscular scoliosis Neuromyelitis optica spectrum disorder Neuropathic arthropathy Neuropathic pruritus Neuropathy peripheral Neuropathy, ataxia, retinitis pigmentosa syndrome Neuropsychiatric symptoms Neurosis New daily persistent headache Nicotine dependence Nipple pain Nocturia Notalgia paraesthetica OBSESSIVE RUMINATION OBSESSIVE THOUGHTS OBSESSIVE-COMPULSIVE DISORDER OBSESSIVE-COMPULSIVE PERSONALITY DISORDER OBSTRUCTION OCCIPITAL NEURALGIA OCULAR DISCOMFORT OEDEMA PERIPHERAL OESOPHAGEAL SPASM OFF LABEL USE OPPOSITIONAL DEFIANT DISORDER OPTIC NEURITIS ORAL DISCOMFORT ORAL LICHEN PLANUS ORAL PAIN OROPHARYNGEAL PAIN OSTEITIS DEFORMANS OSTEOARTHRITIS OSTEOCHONDROSIS OSTEOPOROSIS OSTEOSARCOMA OVERDOSE Obsessive-compulsive disorder Occipital neuralgia Oesophageal motility disorder Oesophageal pain Off label use Oral dysaesthesia Oropharyngeal pain Orthopaedic procedure Orthostatic headache Orthostatic intolerance Osteoarthritis Osteopenia Osteoporosis Ovarian cancer Overdose PAIN PAIN IN EXTREMITY PAIN IN JAW PAIN MANAGEMENT PAIN OF EXTREMITIES PAIN PROPHYLAXIS PAIN THRESHOLD DECREASED PAINFUL FEET PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME PALPITATIONS PANIC ATTACK PANIC DISORDER PANIC DISORDER WITH AGORAPHOBIA PANIC DISORDER WITHOUT AGORAPHOBIA PANIC DISORDER/ DEPRESSION PANIC REACTION PARAESTHESIA PARALYSIS PARAMNESIA PARANOIA PARAPLEGIA PARKINSON'S DISEASE PARKINSON^S DISEASE PELVIC DISCOMFORT PELVIC FLOOR DYSSYNERGIA PELVIC PAIN PERIARTHRITIS PERINATAL DEPRESSION PERIPHERAL ARTERIAL OCCLUSIVE DISEASE PERIPHERAL MOTOR NEUROPATHY PERIPHERAL SENSORIMOTOR NEUROPATHY PERIPHERAL SENSORY NEUROPATHY PERIPHERAL SWELLING PERIPHERAL VASCULAR DISORDER PERIPHERAL VENOUS DISEASE PERONEAL MUSCULAR ATROPHY PERSISTENT DEPRESSIVE DISORDER PERSONALITY DISORDER PHAGOPHOBIA PHANTOM LIMB SYNDROME PHANTOM PAIN PHIMOSIS PHOBIA PHOTOSENSITIVITY REACTION PIRIFORMIS SYNDROME PLANTAR FASCIITIS PLASMA CELL MYELOMA POISONING DELIBERATE POLIOMYELITIS POLLAKIURIA POLYARTHRITIS POLYCYSTIC OVARIES POLYCYTHEMIA VERA POLYMYALGIA RHEUMATICA POLYMYOSITIS POLYNEUROPATHY POLYNEUROPATHY IN MALIGNANT DISEASE POLYOMAVIRUS-ASSOCIATED NEPHROPATHY POLYSUBSTANCE ABUSE POOR PERIPHERAL CIRCULATION POOR QUALITY SLEEP PORPHYRIA ACUTE POST BREAST THERAPY PAIN SYNDROME POST CONCUSSION SYNDROME POST HERPETIC NEURALGIA POST LAMINECTOMY SYNDROME POST POLIO SYNDROME POST PROCEDURAL COMPLICATION POST STROKE DEPRESSION POST VIRAL FATIGUE SYNDROME POST-TRAUMATIC HEADACHE POST-TRAUMATIC NEURALGIA POST-TRAUMATIC PAIN POST-TRAUMATIC STRESS DISORDER POSTOPERATIVE ANALGESIA POSTPARTUM ANXIETY POSTPARTUM DEPRESSION POSTPARTUM DISORDER POSTPARTUM STRESS DISORDER POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME POTENTIATING DRUG INTERACTION PRE-EXISTING DISEASE PREGNANCY PREMEDICATION PREMENSTRUAL DYSPHORIC DISORDER PREMENSTRUAL SYNDROME PROCEDURAL ANXIETY PROCEDURAL PAIN PROCTALGIA PRODUCT ADMINISTRATION ERROR PRODUCT PRESCRIBING ERROR PRODUCT SUBSTITUTION ISSUE PRODUCT USE IN UNAPPROVED INDICATION PRODUCT USE ISSUE PRODUCT USED FOR UNKNOWN INDICATION PROPHYLAXIS PROPHYLAXIS OF NAUSEA AND VOMITING PRURITUS PSORIASIS PSORIATIC ARTHROPATHY PSYCHIATRIC SYMPTOM PSYCHOMOTOR HYPERACTIVITY PSYCHOSOMATIC DISEASE PSYCHOTHERAPY PSYCHOTIC BEHAVIOUR PSYCHOTIC DISORDER PSYCHOTIC SYMPTOM PUDENDAL CANAL SYNDROME PULMONARY OEDEMA PYODERMA GANGRENOSUM Pain Pain in extremity Pain in jaw Pain management Pain prophylaxis Palliative care Palliative sedation Palmar-plantar erythrodysaesthesia syndrome Pancreatic carcinoma Panic attack Panic disorder Papule Paraesthesia Paranoia Parasomnia Parkinson^s disease Parkinsonism Pelvic pain Periarthritis Perinatal depression Peripheral coldness Peripheral nerve injury Peripheral nerve lesion Peripheral sensorimotor neuropathy Peripheral sensory neuropathy Peripheral swelling Peripheral vascular disorder Persistent depressive disorder Persistent genital arousal disorder Persistent postural-perceptual dizziness Personality disorder Phagophobia Phantom limb syndrome Phlebitis Piriformis syndrome Plasma cell myeloma Plasmacytoma Pneumocystis jirovecii pneumonia Pneumonia Poisoning deliberate Polymyalgia rheumatica Polyneuropathy Polyneuropathy in malignant disease Poor quality sleep Post breast therapy pain syndrome Post concussion syndrome Post herpetic neuralgia Post lumbar puncture syndrome Post viral fatigue syndrome Post-acute COVID-19 syndrome Post-traumatic headache Post-traumatic neuralgia Post-traumatic stress disorder Premedication Premenstrual dysphoric disorder Premenstrual syndrome Preoperative care Procedural pain Product administration error Product administration interrupted Product use in unapproved indication Product use issue Product used for unknown indication Prophylaxis Prophylaxis against alcoholic withdrawal syndrome Prostate cancer Prostatic disorder Pruritus Psoriasis Psoriatic arthropathy Psychiatric care Psychiatric symptom Psychosis postoperative Psychosocial support Psychotherapy Psychotic disorder Psychotic symptom Pudendal canal syndrome Pulmonary arterial hypertension Pyelonephritis acute Pyrexia Quality of life decreased RADICULAR PAIN RADICULOPATHY RASH RAYNAUD'S PHENOMENON RAYNAUD^S PHENOMENON REACTIVE DEPRESSION RELAPSING-REMITTING MULTIPLE SCLEROSIS RELAXATION THERAPY RENAL DISORDER REPETITIVE STRAIN INJURY RESPIRATORY DEPRESSION RESTLESS LEGS SYNDROME RESTLESSNESS RETROPERITONEAL FIBROSIS RHEUMATIC DISORDER RHEUMATOID ARTHRITIS RHEUMATOID FACTOR ROAD TRAFFIC ACCIDENT ROTATOR CUFF SYNDROME ROUTINE HEALTH MAINTENANCE Radiation associated pain Radicular pain Radiculopathy Rapid eye movements sleep abnormal Rash Relapsing-remitting multiple sclerosis Relaxation therapy Restless legs syndrome Restlessness Rheumatic disorder Rheumatoid arthritis Road traffic accident Rotator cuff syndrome SACROILIITIS SCAPULA FRACTURE SCHIZOAFFECTIVE DISORDER SCHIZOAFFECTIVE DISORDER BIPOLAR TYPE SCHIZOAFFECTIVE DISORDER DEPRESSIVE TYPE SCHIZOPHRENIA SCHIZOPHRENIA, DISORGANISED TYPE SCHIZOPHRENIA, PARANOID TYPE SCHIZOPHRENIA, RESIDUAL TYPE SCHOOL REFUSAL SCIATIC NERVE INJURY SCIATIC NERVE NEUROPATHY SCIATICA SCLERODERMA SCOLIOSIS SEASONAL AFFECTIVE DISORDER SECONDARY ADRENOCORTICAL INSUFFICIENCY SEDATION SEDATIVE THERAPY SEIZURE SELF INJURIOUS BEHAVIOUR SENILE ANKYLOSING VERTEBRAL HYPEROSTOSIS SENSORY DISTURBANCE SENSORY LOSS SERONEGATIVE ARTHRITIS SEROTONIN SYNDROME SERUM SEROTONIN DECREASED SERUM SEROTONIN INCREASED SHOULDER PAIN SICK RELATIVE SJOGREN'S SYNDROME SJOGREN^S SYNDROME SKELETAL INJURY SKIN BURNING SENSATION SKIN DISORDER SKIN LESION SKIN ULCER SLEEP APNOEA SYNDROME SLEEP DISORDER SLEEP DISORDER THERAPY SLEEP TERROR SMALL FIBRE NEUROPATHY SMOKING CESSATION THERAPY SOCIAL ANXIETY DISORDER SOCIAL PHOBIA SOFT TISSUE DISORDER SOMATIC DYSFUNCTION SOMATIC SYMPTOM DISORDER SOMATISATION DISORDER SOMATOFORM DISORDER SOMATOSENSORY EVOKED POTENTIALS SOMNOLENCE SPINAL COLUMN INJURY SPINAL COLUMN STENOSIS SPINAL COMPRESSION FRACTURE SPINAL CORD COMPRESSION SPINAL CORD DISORDER SPINAL CORD INJURY SPINAL CORD NEOPLASM SPINAL DECOMPRESSION SPINAL DEFORMITY SPINAL DISORDER SPINAL OPERATION SPINAL OSTEOARTHRITIS SPINAL PAIN SPINAL STENOSIS SPINE MALFORMATION SPINOCEREBELLAR ATAXIA SPONDYLITIS SPONDYLOLISTHESIS SPONDYLOLYSIS STRESS STRESS AT WORK STRESS INCONTINENCE STRESS SYMPTOMS STRESS URINARY INCONTINENCE SUBSTANCE DEPENDENCE SUBSTANCE USE SUICIDAL IDEATION SUICIDE ATTEMPT SUNCT SYNDROME SUNCT syndrome SUPPLEMENTATION THERAPY SURGERY SUSPECTED SUICIDE SWELLING SYMPTOMATIC TREATMENT SYNCOPE SYRINGOMYELIA SYSTEMIC LUPUS ERYTHEMATOSUS Sacroiliitis Schizoaffective disorder Schizoaffective disorder bipolar type Schizophrenia Schizotypal personality disorder Sciatica Scleroderma Scoliosis Seasonal affective disorder Secondary progressive multiple sclerosis Sedative therapy Seizure Self-destructive behaviour Sensory disturbance Sensory ganglionitis Sensory loss Serotonin deficiency Sickle cell anaemia with crisis Sickle cell disease Sjogren^s syndrome Skin disorder Sleep disorder Sleep disorder therapy Small fibre neuropathy Small intestinal obstruction Social anxiety disorder Somatic dysfunction Somatic symptom disorder Somniphobia Speech disorder Sphincter of Oddi dysfunction Spinal compression fracture Spinal cord injury Spinal disorder Spinal fracture Spinal operation Spinal osteoarthritis Spinal pain Spinal stenosis Spondylitis Spondyloarthropathy Spondylolisthesis Stiff person syndrome Stress Stress urinary incontinence Substance abuse Substance use Suicidal ideation Suicide attempt Supplementation therapy Supraventricular tachycardia Suspected suicide Swelling of eyelid Symptomatic treatment Syncope Systemic lupus erythematosus Systemic scleroderma TACHYCARDIA TARDIVE DYSKINESIA TARSAL TUNNEL SYNDROME TEMPOROMANDIBULAR JOINT SYNDROME TENDON DISORDER TENDONITIS TENSION TENSION HEADACHE TESTICULAR PAIN THERAPY CESSATION THERAPY CHANGE THINKING ABNORMAL THORACIC OUTLET SYNDROME THYROID DISORDER TINNITUS TOBACCO USER TOOTHACHE TORTICOLLIS TOURETTE^S DISORDER TOXICITY TO VARIOUS AGENTS TRANSIENT ISCHAEMIC ATTACK TREMOR TRIGEMINAL NERVE DISORDER TRIGEMINAL NEURALGIA TUMOUR PAIN TYPE 2 DIABETES MELLITUS TYPHOID FEVER Tachycardia Tenderness Tendonitis Tension Tension headache Thymus disorder Thyroid disorder Tic Tinnitus Tooth infection Torticollis Toxicity to various agents Treatment failure Tremor Trichodynia Trigeminal neuralgia Trigeminal neuropathy Triple negative breast cancer Trisomy 21 Tumour thrombosis Type 2 diabetes mellitus ULCER ULCER HAEMORRHAGE ULNAR TUNNEL SYNDROME UNEVALUABLE EVENT UPPER MOTOR NEURONE LESION URINARY INCONTINENCE URINARY RETENTION URINARY TRACT DISORDER URINARY TRACT INFECTION URTICARIA UTERINE LEIOMYOMA Ulnar nerve injury Unevaluable event Upper motor neurone lesion Urge incontinence Urinary incontinence Urinary tract infection Urticaria VASCULAR PAIN VASCULAR PARKINSONISM VASCULITIS VERTEBRAL FORAMINAL STENOSIS VERTEBRAL INJURY VERTIGO VESTIBULAR DISORDER VESTIBULITIS VIBRATORY SENSE INCREASED VIITH NERVE PARALYSIS VIOLENCE-RELATED SYMPTOM VIRAL INFECTION VISUAL IMPAIRMENT VOMITING VULVOVAGINAL DISCOMFORT VULVOVAGINAL DRYNESS VULVOVAGINAL PAIN Vasculitis Vestibular disorder Vestibular migraine Visceral pain Vision blurred Vitamin D deficiency Vomiting Vulvovaginal pain WEIGHT WEIGHT CONTROL WEIGHT DECREASED WEIGHT INCREASED WITHDRAWAL SYNDROME West Nile viral infection Withdrawal syndrome Wound complication Duloxetine brand names and reporting trend
Duloxetine is sold under the brand name Cymbalta.
Quarterly reports (2004–2025) An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
Taking duloxetine with another medication? Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.
