OpenClaim

Dronabinol Side Effects

The most commonly reported side effects of dronabinol include nausea, fatigue, and death, based on 8,336 FDA adverse event reports from 2004 to 2025. 3.9% of reports found the drug to be ineffective.

Dronabinol side effects

Percentages show how often each reaction appears relative to total reports for dronabinol.

1
Nausea9.7%810
2
Fatigue8.2%682
3
Death7.4%613
4
Diarrhoea6.9%574
5
Off Label Use6.3%529
6
Vomiting6.1%507
7
Decreased Appetite5.6%467
8
Weight Decreased4.8%404
9
Pain4.8%400
10
Asthenia4.1%340
11
Dyspnoea4.0%337
12
Drug Ineffective3.9%329
13
Toxicity To Various Agents3.6%299
14
Headache3.6%298
15
Drug Abuse3.4%284

These are voluntary reports and do not establish that dronabinol caused these reactions.

Report severity

74.6%Serious6,217 reports
38.8%Hospitalizations3,237 reports
21.1%Fatal1,755 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dronabinol drug interactions

Other drugs that appear in adverse event reports alongside dronabinol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide8.0%664
2
Fentanyl3.3%279
3
Capecitabine2.8%234
4
Diazepam2.6%218
5
Oxycodone2.4%201
6
Sodium-oxybate2.4%198
7
Paclitaxel2.2%187
8
Cabozantinib2.2%187
9
Pregabalin2.2%183
10
Methadone-hydrochloride2.0%163
11
Pomalidomide1.9%162
12
Tenofovir1.9%156
13
Trastuzumab1.8%154
14
Bevacizumab1.8%151
15
Nivolumab1.8%151

Taken alongside

1
Ondansetron27.8%2,319
2
Acetaminophen24.4%2,037
3
Oxycodone19.0%1,581
4
Gabapentin15.2%1,267
5
Pantoprazole-sodium14.8%1,236
6
Ergocalciferol14.4%1,203
7
Lorazepam14.2%1,185
8
Dexamethasone14.0%1,166
9
Aspirin13.1%1,094
10
Omeprazole13.0%1,080
11
Albuterol12.4%1,035
12
Levothyroxine-sodium12.0%1,001
13
Prochlorperazine11.5%958
14
Acyclovir10.2%848
15
Furosemide10.0%836

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dronabinol side effects

45.4% of dronabinol adverse event reports involve female patients and 48.7% involve male patients. The largest age group is adult at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.4%
Male48.7%
Unknown5.9%

Age group

< 20.5%
2–111.3%
12–172.9%
18–6463.0%
65+32.2%

What is dronabinol used for

Conditions and purposes for which patients were taking dronabinol when the adverse event was reported.

Abdominal PainAbnormal Loss Of WeightAccidental ExposureAccidental Exposure To ProductAcquired Immunodeficiency SyndromeAcute Myeloid LeukaemiaAdjuvant TherapyAdverse EventAggressionAgitationAmyotrophic Lateral SclerosisAnalgesic TherapyAnorexiaAntiemetic Supportive CareAnxiety

Showing 15 of 261 indications

Dronabinol brand names and reporting trend

Dronabinol is sold under the brand name Dronabinol.

Brand names

Dronabinol5,677

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dronabinol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.