OpenClaim

Doxapram Side Effects

The most commonly reported side effects of doxapram include hypokalaemia, coagulopathy, and drug interaction, based on 74 FDA adverse event reports from 2004 to 2025.

#1 Reported: HypokalaemiaAll side effects ↓Top Co-Medication: CaffeineDrug interactions ↓45% of Reports Are AdultDemographics ↓

Doxapram side effects

Percentages show how often each reaction appears relative to total reports for doxapram.

1
Hypokalaemia20.3%15
2
Coagulopathy6.8%5
3
Drug Interaction6.8%5
4
Depressed Level Of Consciousness6.8%5
5
Respiratory Failure5.4%4
6
Atrial Fibrillation4.1%3
7
Hepatic Failure4.1%3
8
Hepatitis Fulminant4.1%3
9
Dyspnoea4.1%3
10
Respiratory Failure4.1%3
11
Vomiting4.1%3
12
Delayed Recovery From Anaesthesia2.7%2
13
Haemorrhage2.7%2
14
Respiratory Depression2.7%2
15
Cardiac Failure2.7%2

These are voluntary reports and do not establish that doxapram caused these reactions.

Report severity

93.2%Serious69 reports
39.2%Hospitalizations29 reports
17.6%Fatal13 reports

Seriousness is determined by the reporter, not by OpenClaim.

Doxapram drug interactions

Other drugs that appear in adverse event reports alongside doxapram. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Caffeine14.9%11
2
Hydrochlorothiazide12.2%9
3
Furosemide12.2%9
4
Propofol9.5%7
5
Spironolactone9.5%7
6
Albuterol6.8%5
7
Nifedipine6.8%5
8
Beclomethasone6.8%5
9
Diclofenac5.4%4
10
Tranexamic-acid5.4%4
11
Codeine4.1%3
12
Esomeprazole4.1%3
13
Nitric-oxide4.1%3
14
Erythromycin4.1%3
15
Cefmetazole-sodium4.1%3

Taken alongside

1
Furosemide16.2%12
2
Caffeine12.2%9
3
Insulin10.8%8
4
Acetaminophen10.8%8
5
Vancomycin9.5%7
6
Omeprazole8.1%6
7
Fentanyl8.1%6
8
Albuterol8.1%6
9
Amlodipine8.1%6
10
Aspirin8.1%6
11
Ibuprofen6.8%5
12
Prednisone6.8%5
13
Dexamethasone6.8%5
14
Oxycodone6.8%5
15
Ondansetron6.8%5

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports doxapram side effects

58.1% of doxapram adverse event reports involve female patients and 36.5% involve male patients. The largest age group is adult at 45%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.1%
Male36.5%
Unknown5.4%

Age group

< 233.9%
2–110.0%
12–170.0%
18–6444.6%
65+21.4%

What is doxapram used for

Conditions and purposes for which patients were taking doxapram when the adverse event was reported.

Abdominal DiscomfortAnaesthesiaApnoeaApnoea NeonatalApnoeic AttackBradycardiaDrug TherapyDrug Use For Unknown IndicationExtubationHypercapniaImpaired Gastric EmptyingInfantile ApnoeaNauseaNeonatal Respiratory Distress SyndromeProduct Used For Unknown Indication

Showing 15 of 23 indications

Doxapram brand names and reporting trend

Quarterly reports (2004–2025)

200520102025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking doxapram with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

Check my medications