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Dostarlimab Side Effects

The most commonly reported side effects of dostarlimab include malignant neoplasm progression, off label use, and rash, based on 1,743 FDA adverse event reports from 2005 to 2025.

Dostarlimab side effects

Percentages show how often each reaction appears relative to total reports for dostarlimab.

1
Malignant Neoplasm Progression10.2%178
2
Off Label Use6.2%108
3
Rash5.0%88
4
Fatigue4.4%77
5
Thrombocytopenia4.0%70
6
Anaemia4.0%70
7
Death3.8%66
8
Diarrhoea3.7%64
9
Arthralgia3.2%55
10
Pyrexia3.1%54
11
Neuropathy Peripheral2.9%51
12
Nausea2.6%46
13
Condition Aggravated2.6%46
14
Dyspnoea2.5%44
15
Hypothyroidism2.3%40

These are voluntary reports and do not establish that dostarlimab caused these reactions.

Report severity

86.5%Serious1,508 reports
39.1%Hospitalizations682 reports
12.3%Fatal214 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dostarlimab drug interactions

Other drugs that appear in adverse event reports alongside dostarlimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Paclitaxel43.0%749
2
Carboplatin42.7%745
3
Niraparib-tosylate8.2%143
4
Bevacizumab6.8%119
5
Docetaxel1.8%31
6
Pemetrexed0.9%16
7
Pembrolizumab0.8%14
8
Doxorubicin-hydrochloride0.8%14
9
Pegfilgrastim0.7%13
10
Methylprednisolone0.7%13
11
Cyclophosphamide0.6%11
12
Acetaminophen0.6%10
13
Paroxetine0.6%10
14
Prazepam0.6%10
15
Gabapentin0.6%10

Taken alongside

1
Carboplatin4.9%85
2
Cisplatin4.6%81
3
Docetaxel4.6%81
4
Paclitaxel4.2%74
5
Ondansetron4.2%73
6
Levothyroxine-sodium3.7%64
7
Acetaminophen2.8%48
8
Aprepitant2.5%43
9
Omeprazole2.4%41
10
Dexamethasone2.1%37
11
Prednisone1.7%30
12
Methylprednisolone1.7%30
13
Prochlorperazine1.7%30
14
Dexchlorpheniramine-maleate1.7%29
15
Metformin1.6%28

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dostarlimab side effects

61.8% of dostarlimab adverse event reports involve female patients and 3.7% involve male patients. The largest age group is elderly at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.8%
Male3.7%
Unknown34.5%

Age group

< 20.0%
2–110.1%
12–170.0%
18–6441.8%
65+58.1%

What is dostarlimab used for

Conditions and purposes for which patients were taking dostarlimab when the adverse event was reported.

Adenocarcinoma PancreasAdenocarcinomaAdenocarcinoma Of ColonAdrenal InsufficiencyAdrenocortical CarcinomaAnal CancerBreast CancerBreast Cancer FemaleBile Duct CancerBiopsy EndometriumBladder Transitional Cell CarcinomaBreast CancerBreast Cancer MetastaticBronchial CarcinomaCervix Carcinoma

Showing 15 of 110 indications

Dostarlimab brand names and reporting trend

Dostarlimab is sold under the brand name Jemperli.

Brand names

Jemperli1,924

Quarterly reports (20052025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dostarlimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.