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Doripenem Side Effects

The most commonly reported side effects of doripenem include pneumonia, convulsion, and sepsis, based on 799 FDA adverse event reports from 2006 to 2025. 4.9% of reports found the drug to be ineffective.

Doripenem side effects

Percentages show how often each reaction appears relative to total reports for doripenem.

1
Pneumonia6.0%48
2
Drug Ineffective4.9%39
3
Convulsion4.8%38
4
Sepsis4.8%38
5
Pneumonia4.8%38
6
Pyrexia4.6%37
7
Sepsis3.8%30
8
Off Label Use3.3%26
9
Pyrexia3.1%25
10
Febrile Neutropenia2.5%20
11
Multiple Organ Dysfunction Syndrome2.3%18
12
Platelet Count Decreased2.1%17
13
Renal Failure Acute2.1%17
14
Multi-organ Failure2.1%17
15
Death2.1%17

These are voluntary reports and do not establish that doripenem caused these reactions.

Report severity

96.4%Serious770 reports
41.7%Hospitalizations333 reports
42.9%Fatal343 reports

Seriousness is determined by the reporter, not by OpenClaim.

Doripenem drug interactions

Other drugs that appear in adverse event reports alongside doripenem. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Vancomycin6.5%52
2
Meropenem5.5%44
3
Amphotericin-b4.9%39
4
Azacitidine4.4%35
5
Methylprednisolone4.0%32
6
Linezolid3.8%30
7
Tacrolimus3.0%24
8
Prednisolone3.0%24
9
Piperacillin2.6%21
10
Metronidazole2.6%21
11
Dexamethasone2.6%21
12
Levofloxacin2.5%20
13
Fluconazole2.4%19
14
Methotrexate2.3%18
15
Amikacin-sulfate2.1%17

Taken alongside

1
Vancomycin14.6%117
2
Methylprednisolone13.1%105
3
Furosemide12.6%101
4
Meropenem12.4%99
5
Cefepime-hydrochloride10.8%86
6
Levofloxacin10.5%84
7
Fluconazole9.4%75
8
Acetaminophen9.4%75
9
Acyclovir8.5%68
10
Prednisolone8.3%66
11
Insulin8.1%65
12
Piperacillin7.9%63
13
Voriconazole7.6%61
14
Micafungin-sodium7.6%61
15
Omeprazole7.5%60

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports doripenem side effects

41.3% of doripenem adverse event reports involve female patients and 51.8% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.3%
Male51.8%
Unknown6.9%

Age group

< 20.6%
2–111.7%
12–171.5%
18–6452.6%
65+43.7%

What is doripenem used for

Conditions and purposes for which patients were taking doripenem when the adverse event was reported.

Abdominal AbscessAbdominal InfectionAbdominal SepsisAcinetobacter InfectionAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAcute TonsillitisAdverse EventAgranulocytosisAllergy TestAnti-infective TherapyAntibiotic ProphylaxisAntibiotic TherapyAntifungal ProphylaxisAntifungal Treatment

Showing 15 of 144 indications

Doripenem brand names and reporting trend

Doripenem is sold under the brand name Doribax.

Brand names

Doribax740

Quarterly reports (20062025)

20062010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking doripenem with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.