OpenClaim

Donidalorsen Side Effects

The most commonly reported side effects of donidalorsen include dyspnoea, drug hypersensitivity, and rib fracture, based on 7 FDA adverse event reports from 2015 to 2025.

Donidalorsen side effects

Percentages show how often each reaction appears relative to total reports for donidalorsen.

1
Dyspnoea14.3%1
2
Drug Hypersensitivity14.3%1
3
Rib Fracture14.3%1
4
Chest Injury14.3%1
5
Fall14.3%1
6
Chest Pain14.3%1
7
Peripheral Swelling14.3%1
8
Injection Site Bruising14.3%1
9
Swelling14.3%1
10
Hereditary Angioedema14.3%1

These are voluntary reports and do not establish that donidalorsen caused these reactions.

Report severity

14.3%Serious1 reports
0.0%Hospitalizations0 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Donidalorsen drug interactions

Other drugs that appear in adverse event reports alongside donidalorsen. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Abiraterone-acetate14.3%1
2
Mesalamine14.3%1
3
Venlafaxine14.3%1
4
Ezetimibe14.3%1
5
Simvastatin14.3%1
6
Acetaminophen14.3%1
7
Propoxyphene14.3%1
8
Pregabalin14.3%1
9
Aspirin14.3%1
10
Trazodone-hydrochloride14.3%1
11
Tiotropium-bromide14.3%1
12
Hydroxychloroquine-sulfate14.3%1
13
Azelastine14.3%1
14
Rofecoxib14.3%1
15
Mometasone-furoate14.3%1

Taken alongside

1
Aspirin28.6%2
2
Magnesium-acetate-tetrahydrate28.6%2
3
Ergocalciferol28.6%2
4
Chlorthalidone14.3%1
5
Triamcinolone14.3%1
6
Calcium14.3%1
7
Dutasteride14.3%1
8
Leuprolide14.3%1
9
Diphenhydramine14.3%1
10
Fluconazole14.3%1
11
Venlafaxine14.3%1
12
Tramadol-hydrochloride14.3%1
13
Rosuvastatin14.3%1
14
Cyanocobalamin14.3%1
15
Ascorbic-acid14.3%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports donidalorsen side effects

14.3% of donidalorsen adverse event reports involve female patients and 28.6% involve male patients. The largest age group is adult at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female14.3%
Male28.6%
Unknown57.1%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6457.1%
65+42.9%

What is donidalorsen used for

Conditions and purposes for which patients were taking donidalorsen when the adverse event was reported.

Hereditary AngioedemaProduct Used For Unknown Indication

Donidalorsen brand names and reporting trend

Donidalorsen is sold under the brand name Dawnzera (autoinjector).

Brand names

Dawnzera (autoinjector)2

Quarterly reports (20152025)

201520162025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking donidalorsen with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.