The most commonly reported side effects of donepezil include fall, death, and diarrhoea, based on 39,271 FDA adverse event reports from 2004 to 2025. 3.7% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for donepezil.
These are voluntary reports and do not establish that donepezil caused these reactions.
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Other drugs that appear in adverse event reports alongside donepezil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
49.7% of donepezil adverse event reports involve female patients and 41.9% involve male patients. The largest age group is elderly at 88%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking donepezil when the adverse event was reported.
Showing 15 of 380 indications
Donepezil is sold under the brand name Memantine Hydrochloride And Donepezil Hydrochloride.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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