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Dolasetron Side Effects

The most commonly reported side effects of dolasetron include death, off label use, and fatigue, based on 1,476 FDA adverse event reports from 2004 to 2025.

Dolasetron side effects

Percentages show how often each reaction appears relative to total reports for dolasetron.

1
Death18.3%270
2
Off Label Use10.8%160
3
Fatigue10.8%159
4
Nausea9.5%140
5
Nausea7.3%108
6
Dyspnoea6.7%99
7
Asthenia6.3%93
8
Pain5.9%87
9
Vomiting5.7%84
10
Vomiting5.4%80
11
Diarrhoea4.9%73
12
Dyspnoea4.7%70
13
Disease Progression4.5%67
14
Alopecia4.5%67
15
Pyrexia4.4%65

These are voluntary reports and do not establish that dolasetron caused these reactions.

Report severity

86.4%Serious1,275 reports
42.3%Hospitalizations625 reports
29.8%Fatal440 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dolasetron drug interactions

Other drugs that appear in adverse event reports alongside dolasetron. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bevacizumab20.5%303
2
Carboplatin8.2%121
3
Docetaxel7.9%116
4
Cetuximab6.6%98
5
Paclitaxel6.1%90
6
Trastuzumab5.5%81
7
Rituximab5.4%79
8
Gemcitabine5.1%76
9
Capecitabine4.7%70
10
Oxaliplatin4.6%68
11
Zoledronic-acid3.9%58
12
Cyclophosphamide3.8%56
13
Cisplatin3.7%54
14
Erlotinib-hydrochloride3.5%52
15
Doxorubicin-hydrochloride3.4%50

Taken alongside

1
Dexamethasone60.3%890
2
Diphenhydramine32.8%484
3
Acetaminophen30.7%453
4
Lorazepam17.4%257
5
Ondansetron14.4%213
6
Prochlorperazine13.8%204
7
Oxycodone12.6%186
8
Furosemide11.0%163
9
Darbepoetin-alfa10.5%155
10
Palonosetron-hydrochloride9.7%143
11
Cyclophosphamide9.6%141
12
Hydrocodone9.5%140
13
Promethazine-hydrochloride8.7%129
14
Ranitidine8.6%127
15
Fentanyl8.5%126

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dolasetron side effects

58.0% of dolasetron adverse event reports involve female patients and 39.0% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.0%
Male39.0%
Unknown3.0%

Age group

< 2<0.1%
2–110.5%
12–170.4%
18–6467.0%
65+32.0%

What is dolasetron used for

Conditions and purposes for which patients were taking dolasetron when the adverse event was reported.

Adenocarcinoma Of ColonAlcohol Withdrawal SyndromeAnalgesic TherapyAntiemetic Supportive CareAntiallergic TherapyAntibiotic ProphylaxisAntiemetic Supportive CareChemotherapyDrug Use For Unknown IndicationEye OperationHeadacheHodgkin's DiseaseMultiple MyelomaMigraineNausea

Showing 15 of 34 indications

Dolasetron brand names and reporting trend

Dolasetron is sold under the brand name Anzemet.

Brand names

Anzemet415

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dolasetron with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.