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Docetaxel Side Effects

The most commonly reported side effects of docetaxel include alopecia, emotional distress, and anxiety, based on 96,287 FDA adverse event reports from 2004 to 2025.

Docetaxel side effects

Percentages show how often each reaction appears relative to total reports for docetaxel.

1
Alopecia31.0%29,846
2
Emotional Distress8.7%8,423
3
Anxiety7.9%7,597
4
Psychological Trauma7.3%6,982
5
Madarosis7.2%6,900
6
Hair Texture Abnormal6.5%6,222
7
Hair Colour Changes6.3%6,096
8
Pain6.3%6,026
9
Diarrhoea6.0%5,744
10
Hair Disorder5.9%5,665
11
Nausea4.5%4,298
12
Fatigue4.1%3,935
13
Impaired Quality Of Life3.9%3,719
14
Neutropenia3.4%3,281
15
Malignant Neoplasm Progression3.2%3,125

These are voluntary reports and do not establish that docetaxel caused these reactions.

Report severity

82.3%Serious79,215 reports
28.2%Hospitalizations27,115 reports
12.4%Fatal11,949 reports

Seriousness is determined by the reporter, not by OpenClaim.

Docetaxel drug interactions

Other drugs that appear in adverse event reports alongside docetaxel. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Trastuzumab18.7%17,994
2
Pertuzumab10.6%10,237
3
Carboplatin8.6%8,239
4
Cyclophosphamide7.8%7,463
5
Fluorouracil6.5%6,226
6
Cisplatin5.6%5,359
7
Capecitabine4.4%4,241
8
Epirubicin-hydrochloride4.2%3,997
9
Paclitaxel4.0%3,814
10
Doxorubicin-hydrochloride4.0%3,808
11
Gemcitabine3.9%3,801
12
Bevacizumab3.8%3,701
13
Pegfilgrastim2.8%2,701
14
Oxaliplatin2.7%2,581
15
Zoledronic-acid2.3%2,167

Taken alongside

1
Cyclophosphamide13.2%12,723
2
Dexamethasone10.0%9,585
3
Carboplatin8.2%7,868
4
Doxorubicin-hydrochloride6.1%5,841
5
Trastuzumab5.5%5,329
6
Acetaminophen5.4%5,170
7
Ondansetron5.2%5,017
8
Omeprazole3.3%3,189
9
Levothyroxine-sodium3.3%3,141
10
Pegfilgrastim3.0%2,913
11
Aspirin2.7%2,565
12
Metformin2.7%2,553
13
Lisinopril2.6%2,479
14
Paclitaxel2.5%2,418
15
Amlodipine2.4%2,340

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports docetaxel side effects

59.0% of docetaxel adverse event reports involve female patients and 22.5% involve male patients. The largest age group is adult at 70%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.0%
Male22.5%
Unknown18.5%

Age group

< 20.1%
2–110.1%
12–170.3%
18–6470.0%
65+29.4%

What is docetaxel used for

Conditions and purposes for which patients were taking docetaxel when the adverse event was reported.

Acinar Cell Carcinoma Of PancreasAcute Kidney InjuryAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAdenocarcinomaAdenocarcinoma GastricAdenocarcinoma LungAdenocarcinoma MetastaticAdenocarcinoma Of ColonAdenocarcinoma Of The CervixAdenocarcinoma PancreasAdenoid Cystic CarcinomaAdenoma BenignAdenosquamous Cell CarcinomaAdenosquamous Cell Lung Cancer

Showing 15 of 1,314 indications

Docetaxel brand names and reporting trend

Docetaxel is sold under the brand name Beizray.

Brand names

Beizray97,399

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking docetaxel with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.