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Dobutamine Side Effects

The most commonly reported side effects of dobutamine include off label use, death, and cardiogenic shock, based on 6,481 FDA adverse event reports from 2004 to 2025. 13.2% of reports found the drug to be ineffective.

Dobutamine side effects

Percentages show how often each reaction appears relative to total reports for dobutamine.

1
Drug Ineffective13.2%853
2
Off Label Use9.2%599
3
Death7.3%470
4
Cardiogenic Shock6.8%442
5
Multiple Organ Dysfunction Syndrome6.4%415
6
Condition Aggravated5.9%385
7
Sepsis5.9%381
8
Renal Failure5.8%373
9
Pain5.2%336
10
General Physical Health Deterioration5.1%332
11
Nausea5.1%330
12
Injury5.0%324
13
Anxiety4.8%309
14
Vomiting4.7%302
15
Unevaluable Event4.6%297

These are voluntary reports and do not establish that dobutamine caused these reactions.

Report severity

93.4%Serious6,054 reports
43.4%Hospitalizations2,815 reports
38.0%Fatal2,462 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dobutamine drug interactions

Other drugs that appear in adverse event reports alongside dobutamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Epinephrine15.6%1,010
2
Heparin9.9%640
3
Amiodarone-hydrochloride9.4%606
4
Vasopressin8.2%534
5
Ceftriaxone-sodium7.4%478
6
Acetaminophen6.7%433
7
Furosemide6.6%427
8
Simvastatin6.3%411
9
Albuterol6.2%401
10
Lansoprazole6.1%398
11
Insulin6.1%396
12
Allopurinol5.8%374
13
Metronidazole5.7%371
14
Aprotinin5.4%351
15
Ondansetron5.3%346

Taken alongside

1
Furosemide20.8%1,347
2
Epinephrine17.9%1,161
3
Heparin13.5%875
4
Dopamine-hydrochloride11.2%724
5
Aspirin10.0%651
6
Fentanyl9.2%596
7
Midazolam9.1%588
8
Vancomycin8.7%561
9
Potassium-chloride8.1%523
10
Insulin8.0%516
11
Spironolactone7.7%499
12
Amiodarone-hydrochloride7.0%454
13
Nitroglycerin6.4%416
14
Acetaminophen6.4%415
15
Milrinone-lactate5.6%365

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dobutamine side effects

36.8% of dobutamine adverse event reports involve female patients and 46.6% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.8%
Male46.6%
Unknown16.6%

Age group

< 27.7%
2–112.3%
12–172.3%
18–6451.0%
65+36.7%

What is dobutamine used for

Conditions and purposes for which patients were taking dobutamine when the adverse event was reported.

Acute Coronary SyndromeAcute Kidney InjuryAcute Left Ventricular FailureAcute Myocardial InfarctionAcute Pulmonary OedemaAcute Respiratory Distress SyndromeAcute Respiratory FailureAdjuvant TherapyAdrenocortical Insufficiency AcuteAdverse EventAnaesthesia ProcedureAnaphylactic ReactionAnaphylactic ShockAngina PectorisAngiogram

Showing 15 of 414 indications

Dobutamine brand names and reporting trend

Dobutamine is sold under the brand name Dobutamine Hydrochloride.

Brand names

Dobutamine Hydrochloride92

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dobutamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.