OpenClaim

Diflorasone Side Effects

The most commonly reported side effects of diflorasone include psoriasis, pruritus, and pain, based on 244 FDA adverse event reports from 2004 to 2025. 4.5% of reports found the drug to be ineffective.

Diflorasone side effects

Percentages show how often each reaction appears relative to total reports for diflorasone.

1
Psoriasis5.7%14
2
Pruritus5.3%13
3
Drug Ineffective4.5%11
4
Pain4.1%10
5
Pyrexia4.1%10
6
Pain4.1%10
7
Nausea4.1%10
8
Nausea3.3%8
9
Vomiting3.3%8
10
Anxiety3.3%8
11
Product Use Issue3.3%8
12
Feeling Abnormal2.9%7
13
Neuropathy Peripheral2.9%7
14
Abdominal Pain2.5%6
15
Off Label Use2.5%6

These are voluntary reports and do not establish that diflorasone caused these reactions.

Report severity

69.7%Serious170 reports
38.1%Hospitalizations93 reports
6.1%Fatal15 reports

Seriousness is determined by the reporter, not by OpenClaim.

Diflorasone drug interactions

Other drugs that appear in adverse event reports alongside diflorasone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate4.5%11
2
Adalimumab4.1%10
3
Enfortumab-vedotin-ejfv3.7%9
4
Etanercept3.3%8
5
Dupilumab3.3%8
6
Drospirenone2.9%7
7
Ethinyl-estradiol2.9%7
8
Doxorubicin-hydrochloride2.5%6
9
Atezolizumab2.5%6
10
Pimecrolimus2.0%5
11
Acetaminophen2.0%5
12
Hydrocodone2.0%5
13
Bortezomib2.0%5
14
Cyclophosphamide2.0%5
15
Lomitapide-mesylate2.0%5

Taken alongside

1
Furosemide18.4%45
2
Acetaminophen16.4%40
3
Aspirin16.0%39
4
Levothyroxine-sodium14.8%36
5
Betamethasone14.3%35
6
Ergocalciferol13.9%34
7
Fluticasone12.7%31
8
Prednisone12.3%30
9
Omeprazole11.5%28
10
Simvastatin11.1%27
11
Amlodipine10.7%26
12
Hydrocortisone10.2%25
13
Lisinopril9.8%24
14
Clobetasol-propionate9.8%24
15
Metoprolol9.0%22

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports diflorasone side effects

48.0% of diflorasone adverse event reports involve female patients and 48.4% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female48.0%
Male48.4%
Unknown3.7%

Age group

< 20.0%
2–111.1%
12–171.1%
18–6453.3%
65+44.5%

What is diflorasone used for

Conditions and purposes for which patients were taking diflorasone when the adverse event was reported.

AtopyBlepharitisDermatitisDermatitis AtopicDermatosisDiarrhoeaDrug Use For Unknown IndicationDermatitisDermatitis AtopicDry SkinEczemaErythema MultiformeErythema NodosumErythema MultiformeGraft Versus Host Disease

Showing 15 of 33 indications

Diflorasone brand names and reporting trend

Diflorasone is sold under the brand name Florone.

Brand names

Florone184

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking diflorasone with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.