OpenClaim

Dicyclomine Side Effects

The most commonly reported side effects of dicyclomine include diarrhoea, nausea, and fatigue, based on 23,529 FDA adverse event reports from 2004 to 2025. 5.4% of reports found the drug to be ineffective.

Dicyclomine side effects

Percentages show how often each reaction appears relative to total reports for dicyclomine.

1
Diarrhoea7.9%1,858
2
Nausea7.8%1,840
3
Fatigue7.4%1,736
4
Pain6.0%1,423
5
Headache5.7%1,344
6
Drug Ineffective5.4%1,270
7
Off Label Use4.9%1,156
8
Vomiting4.3%1,011
9
Abdominal Pain4.3%1,000
10
Dizziness4.2%988
11
Chronic Kidney Disease4.0%950
12
Dyspnoea3.8%900
13
Abdominal Pain Upper3.5%814
14
Anxiety3.4%805
15
Arthralgia3.4%797

These are voluntary reports and do not establish that dicyclomine caused these reactions.

Report severity

60.1%Serious14,150 reports
30.4%Hospitalizations7,162 reports
5.6%Fatal1,313 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dicyclomine drug interactions

Other drugs that appear in adverse event reports alongside dicyclomine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab10.9%2,567
2
Sodium-oxybate4.6%1,078
3
Omeprazole4.4%1,025
4
Esomeprazole4.3%1,017
5
Lenalidomide4.0%934
6
Pantoprazole-sodium3.1%732
7
Lansoprazole2.4%569
8
Infliximab2.3%534
9
Ethinyl-estradiol2.2%511
10
Dupilumab2.2%506
11
Drospirenone2.1%492
12
Pregabalin1.7%396
13
Dexlansoprazole1.5%351
14
Etanercept1.4%337
15
Treprostinil1.3%317

Taken alongside

1
Acetaminophen27.9%6,570
2
Ergocalciferol22.2%5,222
3
Omeprazole21.8%5,126
4
Gabapentin18.7%4,411
5
Albuterol18.7%4,401
6
Ondansetron18.6%4,380
7
Levothyroxine-sodium17.2%4,044
8
Aspirin16.4%3,847
9
Pantoprazole-sodium15.8%3,713
10
Fluticasone15.4%3,630
11
Prednisone14.1%3,323
12
Furosemide12.1%2,846
13
Amlodipine11.9%2,807
14
Atorvastatin-calcium11.8%2,788
15
Metoprolol11.7%2,747

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dicyclomine side effects

72.4% of dicyclomine adverse event reports involve female patients and 21.9% involve male patients. The largest age group is adult at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female72.4%
Male21.9%
Unknown5.7%

Age group

< 2<0.1%
2–110.4%
12–172.1%
18–6466.0%
65+31.5%

What is dicyclomine used for

Conditions and purposes for which patients were taking dicyclomine when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal OperationAbdominal PainAbdominal Pain LowerAbdominal Pain UpperAbdominal RigidityAbdominal TendernessAbnormal FaecesAbscess IntestinalAnal IncontinenceAnalgesic TherapyAntacid TherapyAntibiotic ProphylaxisAntibiotic Therapy

Showing 15 of 339 indications

Dicyclomine brand names and reporting trend

Dicyclomine is sold under the brand name Bentyl.

Brand names

Bentyl29

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dicyclomine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.